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Gernhöfer, Maike; Pawert, Michael; Schramm, Michael; Müller, Ewald F; Triebskorn, Rita

doi:10.1023/a:1012958804442

Cited by 152 publications

(27 citation statements)

References 86 publications

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“…Changes in histology of different tissues are widely used as biomarkers in examination of the health of fish exposed to pesticides content water (Thophon, Kruatrachue, Upathan, Pokethitiyook, Sahaphong, & Jarikhuan, 2003). It can be used in environmental monitoring and allowing examination of target organs, such as gills, kidneys and livers (Gernhofer, Pawet, Schramm, Müller, & Triebskorn, 2001). Blood biochemistry profiles that are also adversely affected by pesticides can be used to assess the stress status of fish.…”

Section: Introductionmentioning

confidence: 99%

Impact of Kinalax EC on Vital Organ Histomorphology, Blood Cell Structure and Brain Acetylcholinesterase Activity in Silver barb (Barbonymus gonionotus)

Akter¹,

Parvin²,

Jahan³

et al. 2019

AquaSt

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The objective of this research was to evaluate the effects of Kinalax 25 EC, an organophosphate pesticide on silver barb (Barbonymus gonionotus). Histological bioassay of gill, liver and kidney of B. gonionotus, RBC count and acetylcholinesterase (AChE) activity were performed to evaluate the effects of the Kinalax 25 EC at cellular and enzymatic levels. The LC50 value of Kinalax 25 EC was estimated as 0.071 ppm for B. gonionotus. The remarkable changes included missing of gill lamellae, gill clubbing, hyperplasia, nuclear hypertrophy, vacuolation, glomerular expansion, increasing the diameter of renal tubules, hemorrhage, necrosis and pyknosis. Several changes in peripheral nuclear erythrocyte included large lymphocyte, dead cell, fusion of cell, binucleated cell, tear-shaped cell, ghost cell, senile cell and abnormal shape of cell were found. The RBC count was significantly higher (P>0.01) in lower doses compared to higher doses of pesticide in B. gonionotus. The level of AChE activities in B. gonionotus brain significantly decreased (P>0.01) in pesticides treated fish compared to control. The result of this study reveals that the synthetic organophosphorus pesticide adversely affects the organ-specific histology, haematology and brain acetylcholinesterase activities of B. gonionotus.

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Section: Introductionmentioning

confidence: 99%

Impact of Kinalax EC on Vital Organ Histomorphology, Blood Cell Structure and Brain Acetylcholinesterase Activity in Silver barb (Barbonymus gonionotus)

Akter¹,

Parvin²,

Jahan³

et al. 2019

AquaSt

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“…E-mail: aaabdelwarith@yahoo.com. changes in the liver. Fish liver histology could therefore serve as a model for studying the interactions between environmental factors and hepatic structures and functions (Hinton and Lauren, 1993;Gernhofer et al, 2001). It has been noted that heavy metals had a negative impact on all relevant parameters and caused histo-pathological changes in fish.…”

Section: Introductionmentioning

confidence: 99%

Effect of zinc toxicity on liver histology of Nile tilapia, Oreochromis niloticus

Abdel-Warith¹,

Younis²,

Al-Asgah³

et al. 2011

Sci. Res. Essays

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In the present study the toxic effects of zinc (Zn) on the liver structure of Nile tilapia, Oreochromis niloticus were investigated. Additionally, we estimated whether Zn concentration and exposure period influence the degree and nature of histological changes in the liver of exposed fish. Two hundred and forty fish (the average weight was 24.30± 2.85 g) were distributed randomly in twenty four glass aquaria (80 L) with stocking density of 10 fish for each. The aquaria were divided into two groups: the first group was exposed to 2, 4 and 6 mg/L of ZnCl 2 which represent 0.25, 0.50 and 0.75 of Zn LC50 respectively for one week (short exposure period); while the second group was exposed to the same concentrations of ZnCl 2 with the same replicates for 4 weeks (long exposure period). In addition, control group were not exposed fish to ZnCl 2 (0.00 LC50) were stocked with three replicates for each period. Fish mortality was significantly increased in a dose-dependent manner, without any significant effect of the exposure duration. Histological changes in the liver included hepatocyte degeneration, nuclear pycnosis, cellular swelling, and congestion of blood vessels. There was a marked difference in these changes among the different treatments of Zn concentrations in addition to the intensity of histological changes were however influenced by the extent of exposure period.

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“…Outra alteração epitelial importante foi o deslocamento epitelial da lamela secundária observado com maior intensidade nos indivíduos coletados em setembro de 2008, constituindo uma das primeiras alterações observadas nas brânquias dos peixes nos caso de exposição aguda a agentes tóxicos (HEATH, 1987;LLOYD 1994) Diversos trabalhos têm demonstrado que as alterações em tecidos branquiais são ferramentas confiáveis e eficientes para detectar e monitorar DPELHQWHV TXH VRIUHP LQÀXrQFLD GH DWLYLGDGHV DQWUySLFDV (TRIEBSKORN, 1998;GERNHÖFER et al, 2001;FRACÁCIO et al, 2003), bem como para prever possíveis riscos ambientais (PEAKALL, 1994;ADAMS et al, 2000). Segundo Laurent e Perry (1991), as alterações morfológicas das brânquias, em resposta a mudanças ambientais, podem representar estratégias adaptativas para conservação de algumas funções ¿VLROyJLFDV Na avaliação ambiental do reservatório, na qual foram utilizados os tecidos branquiais de P. maculatus FRPR ELRPDUFDGRU FROHWDGRV HP MXQKR VHWHPEUR e dezembro de 2008, constatou-se apresentação de alterações mais severas nos indivíduos coletados em setembro e dezembro de 2008 em relação aqueles FROHWDGRV HP MXQKR GH Assim, as lesões histopatológicas observadas indicam que os peixes do presente estudo estão UHVSRQGHQGR DRV HIHLWRV GH [HQRELyWLFRV QmR LGHQWL¿FDGRV presentes na água e no sedimento do reservatório 0DUHFKDO 0DVFDUHQKDV GH 0RUDHV $GHPDLV FRQ¿UPDP D H¿FiFLD GR XVR GDV EUkQTXLDV GD HVSpFLH P. maculatus como biomarcador de contaminação ambiental.…”

Section: As Alterações Foram Mais Severas Nos Indivíduos Coletados Emunclassified

<b>Utilização das brânquias de Pimelodus maculatus (Lacèpéde, 1803) (Siluriformes; Pimelodidae) como biomarcador de poluição no reservatório da UHE Marechal Mascarenhas de Moraes, Minas Gerais, Brasil.</b><br>DOI: 10.5007/2175-7925.2011v24n3p51

et al. 2011

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Untitled

Cited by 152 publications

References 86 publications

Impact of Kinalax EC on Vital Organ Histomorphology, Blood Cell Structure and Brain Acetylcholinesterase Activity in Silver barb (Barbonymus gonionotus)

Impact of Kinalax EC on Vital Organ Histomorphology, Blood Cell Structure and Brain Acetylcholinesterase Activity in Silver barb (Barbonymus gonionotus)

Effect of zinc toxicity on liver histology of Nile tilapia, Oreochromis niloticus

<b>Utilização das brânquias de Pimelodus maculatus (Lacèpéde, 1803) (Siluriformes; Pimelodidae) como biomarcador de poluição no reservatório da UHE Marechal Mascarenhas de Moraes, Minas Gerais, Brasil.</b><br>DOI: 10.5007/2175-7925.2011v24n3p51

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