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N-(2-Nitrooxyethyl)picolinamide

“…For related structures, see: Eremenko et al (1996); Fedorov et al (2001). For further synthetic details, see: Samejima (1960); Jiao et al (1990).…”

Synthesis and antimetastatic activity of metal complexes based on substituted pyridinecarboxylic acid amides and platinum tetrachloride

“…Compounds with a N donor atom in a pyridine ring was used previously by us as ligands to prepare complexes of Pt(II) and Pt(IV) with the goals of modifying cisplatin and preparing new antitumor drugs with reduced toxicity [15,16]. Structures of ligands and complexes that were determined by x-ray structure analysis were reported in these studies.…”

“…An isomer of N- (2-nitroxyethyl)nicotinamide, N-(2-nitroxyethyl)isonicotinamide, gives with K 2 PtCl 4 a complex with the cis-configuration [16]. The reaction of this same ligand with PdCl 2 gives a complex with the trans-configuration [16] (Scheme 3).…”

“…The reaction of this same ligand with PdCl 2 gives a complex with the trans-configuration [16] (Scheme 3).…”

“…A Pd(II) complex in which one of the ligands contains nitroxyethyl and the other, hydroxyethyl, was also synthesized (Scheme 5) [16].…”