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Abstract

Introduction: Essential oils are the perspective source of natural antioxidants because some synthetic antioxidants are now suspected to be potentially harmful to human health. As free radicals can cause inflammatory diseases, cancer, atherosclerosis, and aging, antioxidants can inhibit oxidative chain reactions. Essential oils have a wide range of pharmacological effects as they are multicomponent mixtures of chemical compounds, mainly terpenoids and aromatic components. Materials and Methods: The antioxidant activity of essential oils obtained from aerial parts of Ocimum americanum, Lophanthus anisatus, Monarda fistulosa, and Satureja hortensis (Lamiaceae) has been evaluated spectrophotometrically by 2,2-diphenyl-1-picrylhydrazyl free radical scavenging test. Results: The assessed samples of essential oils reduced the radical from purple to yellowish color reaching 50% of reduction in the range of concentrations from 2.95 to 9.89 mg/ml. The most prominent antioxidant activity was identified for essential oil of M. fistulosa (2.95 mg/ml). The antioxidant activity of four essential oils decreased in such a sequence: M. fistulosa > S. hortensis > L. anisatus > O. americanum. Conclusion: The results of this study suggest the possibility of using the essential oils of four Lamiaceae species as a natural antioxidant sources for the pharmaceutical industry. The antioxidant activities of S. hortensis and M. fistulosa essential oils with dominated phenolic compounds were the most manifested.

Essential Oils from Monarda fistulosa: Chemical Composition and Activation of Transient Receptor Potential A1 (TRPA1) Channels

“…Essential oils of Monarda species have been reported to be rich in oxygenated monoterpenes, leading to differentiation into the following chemotypes: thymol, carvacrol, borneol, and geraniol [10]. A literature survey regarding biological activities of the Monarda species essential oils and their major compounds, based on references [11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29], is summarized in Table 1. Table 1.…”

Natural Compounds and Products from an Anti-Aging Perspective

“…Due to terpenoids, essential oils showed their valuable anti-aging potential in treating anxiety, dementia, and other neurological disorders via in vitro , in vivo , and clinical studies [ 111 , 133 ]. Essential oils are useful as multi-potent agents due to their composition of several valuable components [ 134 , 135 ]. Aromatherapy with essential oils can improve cognitive performance in patients with Alzheimer’s disease [ 133 , 136 ].…”

A Review on Pharmacological Activity of Monarda fistulosa L.

“…Based on the study by Shanaida et al (2018), some active compounds in the EOs of M. fistulosa have a role in its antioxidant activity, such as TQ, flavonoids, thymol, and carvacrol. According to Diaz-Vivancos et al (2015), when TQ is incubated in vitro with methylglyoxal or glucose, it could inhibit the glycation of superoxide dismutase (SOD), as well as maintain its antioxidant activity.…”

“…According to Barreca et al (2017), isosakuranetin is one of the flavanone glycosides that can scavenge free radicals, thus making them function as antioxidants (Panche et al, 2016). Another active compound of M. fistulosa with an antioxidant property is thymol and its isomer, carvacrol (Shanaida et al, 2018). Based on Markovska et al (2020), phenol consisting of thymol and carvacrol comprises about 67-86% of the active compounds of Monarda Eos.…”