Untitled

Matsumiya, Hiroaki; Hoshino, Hitoshi; Yotsuyanagi, Takao

doi:10.1039/b102300b

Cited by 39 publications

(41 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…8 At high pH both HBQ and HBQS chelate specifically with the beryllium ion in a 1:1 ratio to form a sixmembered ring. [8][9][10] The formation of this complex results in a shift in emission spectral characteristics from 575-590 nm to 475-496 nm. [8][9][10] Additionally, when HBQ complexes with the Be (II) ion, the intensity of the fluorescent signal increases by over 10 fold.…”

Section: Introductionmentioning

confidence: 98%

“…[8][9][10] The formation of this complex results in a shift in emission spectral characteristics from 575-590 nm to 475-496 nm. [8][9][10] Additionally, when HBQ complexes with the Be (II) ion, the intensity of the fluorescent signal increases by over 10 fold. The fluorescence intensity has also been shown to be linear in comparison with beryllium concentrations down to the low µg/m 3 .…”

Section: Introductionmentioning

confidence: 98%

“…[8][9][10] The complexity and expense of these methods have driven the investigation into alternate methodologies. The Occupational Safety and Health Administration has set air contaminant exposure general industry at a limit of 2 µg/m 3 for an 8-hour time weighted average.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Nanopillar Based Enhanced-Fluorescence Detection of Surface-Immobilized Beryllium

et al. 2015

View full text Add to dashboard Cite

The unique properties associated with beryllium metal ensures the continued use in many industries despite the documented health and environmental risks. While engineered safeguards and personal protective equipment can reduce risks associated with working with the metal, it has been mandated by the Environmental Protection Agency (EPA) and Occupational Safety and Health Administration (OSHA) that the workplace air and surfaces must be monitored for toxic levels. While many methods have been developed to monitor levels down to the low μg/m(3), the complexity and expense of these methods have driven the investigation into alternate methodologies. Herein, we use a combination of the previously developed fluorescence Be(II) ion detection reagent, 10-hydroxybenzo[h]quinoline (HBQ), with an optical field enhanced silicon nanopillar array, creating a new surface immobilized (si-HBQ) platform. The si-HBQ platform allows the positive control of the reagent for demonstrated reusability and a pillar diameter based tunable enhancement. Furthermore, native silicon nanopillars are overcoated with thin layers of porous silicon oxide to develop an analytical platform capable of a 0.0006 μg/L limit of detection (LOD) using sub-μL sample volumes. Additionally, we demonstrate a method to multiplex the introduction of the sample to the platform, with minimal 5.2% relative standard deviation (RSD) at 0.1 μg/L, to accommodate the potentially large number of samples needed to maintain industrial compliance. The minimal sample and reagent volumes and lack of complex and highly specific instrumentation, as well as positive control and reusability of traditionally consumable reagents, create a platform that is accessible and economically advantageous.

show abstract

Section: Introductionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 98%

See 1 more Smart Citation

Nanopillar Based Enhanced-Fluorescence Detection of Surface-Immobilized Beryllium

et al. 2015

View full text Add to dashboard Cite

show abstract

“…The method is based on the fluorescence of beryllium bound to hydroxybenzoquinoline sulfonate (HBQS) 9 , and includes a dissolution technique using dilute ammonium bifluoride solution 10,11 . Dilute ammonium bifluoride has been proposed as a field extraction medium which is much less hazardous than the strong acids used ordinarily in digestion of beryllium samples in the laboratory.…”

Section: Figmentioning

confidence: 99%

High Sensitivity Low Fluorescence Detection for Beryllium Particulates SBIR Phase I Final Report ER84587

Agrawal¹,

Tonazzi²,

Cronin³

2007

View full text Add to dashboard Cite

“…Of special promise are their biological [1][2][3], photophysical, and coordination [4][5][6][7][8] properties. Their use as chiral catalysts [9,10] is also of interest.…”

mentioning

confidence: 99%

Preparation of (benzo)isoquinolines using in situ generated aryne intermediates

Kopchuk

Zyryanov

Коvalev

et al. 2013

Chem Heterocycl Comp

View full text Add to dashboard Cite

(Benzo)isoquinoline derivatives are of significant interest in different areas of basic and applied organic chemistry. Of special promise are their biological [1][2][3], photophysical, and coordination [4][5][6][7][8] properties. Their use as chiral catalysts [9,10] is also of interest.The most frequently used methods for preparing (benzo)isoquinoline systems are cross-coupling reactions [11,12], which demand the use of special catalysts. We propose a method for preparing (benzo)isoquinoline derivatives based on an aza Diels-Alder reaction with 1,2,4-triazines as dienes and the aryne intermediates acting as dienophiles.The methodology for preparing diverse pyridine derivatives via reaction of the corresponding 1,2,4-triazines has long been known [13][14][15]. However, there are only a few examples of using aryne intermediates in similar reactions. The range of dienophiles in these cases is limited to certain dehydrobenzene derivatives, the generation of which used poorly available anthranilic acids [16,17] despite the marked growth in the chemistry of arynes in recent years [18,19].In our work, we propose a highly efficient method for the preparation of (het)aryl-substituted isoquinoline 1a and benzo[h]isoquinoline 1b, which involves the reaction of arynes 2a,b with the substituted 1,2,4-triazines 3a,b in anhydrous toluene for 24-36 h at 140°C under an argon atmosphere. The target compounds 1a,b were obtained in 76% and 80% yield, respectively. The corresponding arynes were generated in situ by the action of potassium tert-butoxide on the chloro-and bromo-substituted arenes 4a,b.The structure of the obtained compounds 1a,b was confirmed from the 1 H and 13 C NMR spectroscopy, mass spectrometry, and by elemental analysis data. The mass spectra of compounds 1a,b showed the presence of a molecular ion peak.The compounds obtained are 2,2'-bipyridine type ligands with an extended conjugated system, and are of interest from the viewpoint of complex formation and as luminescent materials.

show abstract

Untitled

Cited by 39 publications

References 23 publications

Nanopillar Based Enhanced-Fluorescence Detection of Surface-Immobilized Beryllium

Nanopillar Based Enhanced-Fluorescence Detection of Surface-Immobilized Beryllium

High Sensitivity Low Fluorescence Detection for Beryllium Particulates SBIR Phase I Final Report ER84587

Preparation of (benzo)isoquinolines using in situ generated aryne intermediates

Contact Info

Product

Resources

About