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Stroev, E. A.; Makarova, Valeriya; Ryazanova, E. A.; Plyakhin, I. V.

doi:10.1023/a:1017691113538

Cited by 2 publications

(2 citation statements)

References 5 publications

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“…-acute toxicity (Karber's method; oral single administration of pectin at doses of 10, 100, 1000, 5000 mg/kg, 24 animals [18,19]); -hepatotoxicity of pectins, liquid and solid fractions of vinasse to study sleep duration (Gatsura's method; oral single administration of pectins at a dose of 500 mg/kg or vinasse fractions at a dose of 10-900 mg/kg followed by single intraperitoneal administration of sodium pentabarbital at a dose of 30; 45 mg/kg; control -animals treated with sodium pentabarbital; 24 animals [18,20]); -antiulcerogenic action (oral single administration of acetylsalicylic acid at a dose of 1000 mg/kg followed by oral administration of pectin at a dose of 500 mg/kg per day for a week; control -animals treated with acetylsalicylic acid; 16 animals [20,21]); -content of acidic components of gastric juice (oral single administration of acetylsalicylic acid at a dose of 1000 mg/kg followed by oral administration of pectin at a dose of 500 mg/kg per day for a week; control -animals treated with acetylsalicylic acid; 10 animals [22,23]);…”

Section: Methodsmentioning

confidence: 99%

Processing of after-alcohol vinasse for environmentally friendly environment

Kaishev

Kaisheva

Larsky

et al. 2022

IOP Conf. Ser.: Earth Environ. Sci.

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One of the industrial sources of intoxication polluting the environment is vinasse – a secondary raw material formed during the alcoholic processing of grain in 12 times the volume of alcohol produced. Due to the low content of dry substances (up to 8%), low shelf life (up to 2 days), seasonality of consumption in livestock, the transportation, especially the liquid phase of vinasse, is not economically profitable, which causes the need for its disposal or processing and determines the relevance of this study. Based on the chemical composition of vinasse, the purpose of the study is to study the possibility of obtaining pectins from it as biologically active compounds, which would reduce the volume of vinasse released into the environment thus ensuring its protection. The purpose of the study was fulfilled by solving the following tasks: development of a method of pectins release from vinasse, assessment of their physicochemical and biological properties, determination of chemical and microbiological safety of vinasse wastes. The study included technological, physicochemical, chemical, biological methods. Vinasse fractions were obtained according to the developed method of vinasse processing based on vortex extraction, concentration of extractions, alcohol release of the end products, pectins from liquid (yield 3.1%) and solid (yield 2.9%), which ensured a 20-fold reduction in the volume of vinasse. The characteristics of pectins were established: authenticity, loss in mass during drying, pH, molar mass, content of pectic acid, functional groups, binding properties. The safety and gastroprotective activity of pectins was established. Mother solutions after the release of pectins were estimated to be less than 3.9 times the chemical consumption of oxygen and satisfactory microbiological purity, which made it possible to evaluate them as safe industrial waste.

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Section: Methodsmentioning

confidence: 99%

Processing of after-alcohol vinasse for environmentally friendly environment

Kaishev

Kaisheva

Larsky

et al. 2022

IOP Conf. Ser.: Earth Environ. Sci.

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“…Samples of Wistar rat liver were homogenized (1:10 w/v) in a phosphate buffer, pH 7.4, using a homogenizer. The level of lipid peroxidation was estimated by using the thiobarbituric acid reactive substances (TBARS) assay [53]. The influence of compounds on lipid peroxidation of the rat liver homogenates was carried out at 37 • C in a phosphate buffer (pH 7.4) in the presence or absence of test compounds or vehicles (CHCl 3 ).…”

Section: Lipid Peroxidation Of Rat Liver Homogenatementioning

confidence: 99%

The Synthesis and Biological Activity of Organotin Complexes with Thio-Schiff Bases Bearing Phenol Fragments

Smolyaninov

Poddel’sky

Burmistrova

et al. 2023

IJMS

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A number of novel di- and triorganotin(IV) complexes 1–5 (Ph2SnL1, Ph2SnL2, Et2SnL2, Ph3SnL3, Ph3SnL4) with mono- or dianionic forms of thio-Schiff bases containing antioxidant sterically hindered phenol or catechol fragments were synthesized. Compounds 1–5 were characterized by 1H, 13C NMR, IR spectroscopy, and elemental analysis. The molecular structures of complexes 1 and 2 in the crystal state were established by single-crystal X-ray analysis. The antioxidant activity of new complexes as radical scavengers was estimated in DPPH and ABTS assays. It was found that compounds 4 and 5 with free phenol or catechol fragments are more active in these tests than complexes 1–3 with tridentate O,N,S-coordinated ligands. The effect of compounds 1–5 on the promoted oxidative damage of the DNA by 2,2’-azobis(2-amidinopropane) dihydrochloride and in the process of rat liver (Wistar) homogenate lipid peroxidation in vitro was determined. Complexes 4 and 5 were characterized by more pronounced antioxidant activity in the reaction of lipid peroxidation in vitro than compounds 1–3. The antiproliferative activity of compounds 1–5 was investigated against MCF-7, HTC-116, and A-549 cell lines by an MTT test. The values of IC50 are significantly affected by the presence of free antioxidant fragments and the coordination site for binding.

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Cited by 2 publications

References 5 publications

Processing of after-alcohol vinasse for environmentally friendly environment

Processing of after-alcohol vinasse for environmentally friendly environment

The Synthesis and Biological Activity of Organotin Complexes with Thio-Schiff Bases Bearing Phenol Fragments

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