No abstract

We studied the regulation of calpains in explants from rat thyroid glands. Collagenase disaggregation decreased proteinase activity in thyrocytes. It was hypothesized that this effect is mediated by heterotrimeric G proteins, protein kinase C, and tyrosine kinase, but not via Ca(2+) and cAMP-dependent signal pathway.

Currently, medical technologies based on natural factors are widely used in practical health care, including the effect of the medicinal properties of the mineral silvinite (natural potassium salts of the Verkhnekamsk Deposit) on the patient’s body. However, there is no regulatory framework for sanitary control of such devices. The aim of the study was to develop methodological approaches to the hygienic assessment of silvinite complexes. The analysis of the current regulations used in carrying out hygienic supervision and preventive measures in the salt structures that are part of the silvinite complexes is carried out. Based on long-term hygienic studies of silvinite structures by the salt treatment Center of Perm medical University. academician E. A. Wagner together with LLC NPK «Medical climate» (Tchaikovsky) developed and implemented sanitary and hygienic requirements for the created salt complexes. It is a complex of structural divisions, including the place of stay and treatment of patients, as well as the salt device. All units must meet the requirements of current sanitary rules and regulations. It is necessary to conduct a thorough survey of the location of the future salt complex. Optimal conditions of the internal environment in silvinite structures are determined by a special air preparation system consisting of air conditioning and cleaning of the external air using a filter-saturator. The special hygienic requirements of the sylvinite furniture in the room, the decoration of walls, ceilings and floors. The room must be equipped with radio equipment and a video camera for monitoring patients. Full expanded hygienic control of the parameters of the medical environment of silvinite premises should be carried out at least once a year according to the following indicators: microclimate parameters, content of multicomponent fine salt aerosol, aeroionic composition of the air environment, radiation background, microbial contamination of the internal environment, noise and light levels. Thus, increasing the use of salt therapy requires further research to improve the sanitary and hygienic control of silvinite complexes.

No abstract