A 0.3-V CMOS Biofuel-Cell-Powered Wireless Glucose/Lactate Biosensing System

Yeknami, Ali Fazli; Wang, Xiaoyang; Jeerapan, Itthipon; Imani, Somayeh; Nikoofard, Ali; Wang, Joseph; Mercier, Patrick P.

doi:10.1109/jssc.2018.2869569

Cited by 60 publications

(39 citation statements)

References 32 publications

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“…A possible solution is depicted in Figure 25a [191]. This system uses energy supplied by the BFC and provides glucose/lactate concentration readout and RF data-transmission in the UHF band.…”

Section: Readout Interfaces For Bio-fuel Cellsmentioning

confidence: 99%

“…In this phase, an approximated matched load R MPP is connected to the BFC in order to track the MPP. This need is justified by the authors in [191] by experimental evidence disclosing a linear relationship between the P out and analyte concentration when operating at MPP. A more compact solution for BFC interfacing is proposed in [192] and it is reported in Figure 25b.…”

Section: Readout Interfaces For Bio-fuel Cellsmentioning

confidence: 99%

“…While both reviewed works present pioneer solutions, it is worth noting that [191] fails to address the physiological normal ranges of Table 1. On the other hand, Ref.…”

Section: Readout Interfaces For Bio-fuel Cellsmentioning

confidence: 99%

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CMOS Interfaces for Internet-of-Wearables Electrochemical Sensors: Trends and Challenges

et al. 2019

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Smart wearables, among immediate future IoT devices, are creating a huge and fast growing market that will encompass all of the next decade by merging the user with the Cloud in a easy and natural way. Biological fluids, such as sweat, tears, saliva and urine offer the possibility to access molecular-level dynamics of the body in a non-invasive way and in real time, disclosing a wide range of applications: from sports tracking to military enhancement, from healthcare to safety at work, from body hacking to augmented social interactions. The term Internet of Wearables (IoW) is coined here to describe IoT devices composed by flexible smart transducers conformed around the human body and able to communicate wirelessly. In addition the biochemical transducer, an IoW-ready sensor must include a paired electronic interface, which should implement specific stimulation/acquisition cycles while being extremely compact and drain power in the microwatts range. Development of an effective readout interface is a key element for the success of an IoW device and application. This review focuses on the latest efforts in the field of Complementary Metal–Oxide–Semiconductor (CMOS) interfaces for electrochemical sensors, and analyses them under the light of the challenges of the IoW: cost, portability, integrability and connectivity.

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Section: Readout Interfaces For Bio-fuel Cellsmentioning

confidence: 99%

Section: Readout Interfaces For Bio-fuel Cellsmentioning

confidence: 99%

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CMOS Interfaces for Internet-of-Wearables Electrochemical Sensors: Trends and Challenges

et al. 2019

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“…For example, the power is proportional to the concentration of the fuel (also acting as analyte); self-powered output itself can determine the level of the target. This offers opportunities to eliminate external energy sources for powering potentiostat and signaling systems [9].…”

Section: Enzyme-based Electrochemical Power Sourcesmentioning

confidence: 99%

“…Skin-worn bioelectronics mandates the compliant and efficient energy sources to supply multitasks, including Wearable Skin-Worn Enzyme-Based Electrochemical Devices: Biosensing, Energy Harvesting… DOI: http://dx.doi.org /10.5772/intechopen.85459 sensing and data communication. In addition to developing low-power-consuming electronic microelectronics [9,41], there is an increasing interest in advancing bioenergy-harvesting devices. Enzymatic BFCs are attractive self-sustainable energy devices to meet this growing energy demand.…”

Section: Powering Wearable Devicesmentioning

confidence: 99%

Wearable Skin-Worn Enzyme-Based Electrochemical Devices: Biosensing, Energy Harvesting, and Self-Powered Sensing

Jeerapan¹

2019

Wearable Devices - The Big Wave of Innovation

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Integrating enzymes with wearable electrochemical systems delivers extraordinary functional devices, including biosensors and biofuel cells (BFCs). Strategies employing enzyme-based bioelectronics represent a unique foundation of wearables because of specific enzyme recognition and catalytic activities. Therefore, such electrochemical biodevices on various platforms, e.g., tattoos, textiles, and wearable accessories, are interesting. However, these devices need effective power sources, requiring combining effective energy sources, such as BFCs, onto compact and conformal platforms. Advantageously, bioenergy-harvesting BFCs can also act as self-powered sensors, simplifying wearable systems. Challenges pertaining to energy requirements and the integration of biocatalysts with electrodes should be considered. In this chapter, we detail updated advancement in skin-worn devices, including biosensors, BFCs, and self-powered sensors, along with engineering designs and on-skin iontophoretic strategies to extract biofluids. Crucial parameters including mechanical/material aspects (e.g., stretchability), electrochemistry, enzyme-related views (e.g., electron shuttles, immobilization, and behaviors), and oxygen dependency will be discussed, along with outlooks. Understanding such challenges and opportunities is important to revolutionize wearable devices for diverse applications.

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On‐Body Bioelectronics: Wearable Biofuel Cells for Bioenergy Harvesting and Self‐Powered Biosensing

Jeerapan

Sempionatto

Wang

2019

Adv Funct Materials

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172

113

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The growing power demands of wearable electronic devices have stimulated the development of on-body energy harvesting strategies. This article reviews the recent progress on rapidly emerging wearable biofuel cells (BFCs), along with related challenges and prospects. Advanced on-body BFCs in various wearable platforms, e.g., textiles, patches, temporary tattoo, or contact lenses, have enabled attractive advantages for bioenergy harnessing and self-powered biosensing. These noninvasive BFCs open up unique opportunities for utilizing bioenergy or monitoring biomarkers present in biofluids, e.g., sweat, saliva, interstitial fluid, and tears, toward new biomedical, fitness or defense applications. However, the realization of effective wearable BFC requires high-quality enzymeelectronic interface with efficient enzymatic and electrochemical processes and mechanical flexibility. Understanding the kinetics and mechanisms involved in the electron transfer process, as well as enzyme immobilization techniques, is essential for efficient and stable bioenergy harvesting under diverse mechanical strains and changing operational conditions expected in different biofluids and in a variety of outdoor activities. These key challenges of wearable BFCs are discussed along with potential solutions and future prospects. Understanding these obstacles and opportunities is crucial for transforming traditional bench-top BFCs to effective and successful wearable BFCs.

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A 0.3-V CMOS Biofuel-Cell-Powered Wireless Glucose/Lactate Biosensing System

Cited by 60 publications

References 32 publications

CMOS Interfaces for Internet-of-Wearables Electrochemical Sensors: Trends and Challenges

CMOS Interfaces for Internet-of-Wearables Electrochemical Sensors: Trends and Challenges

Wearable Skin-Worn Enzyme-Based Electrochemical Devices: Biosensing, Energy Harvesting, and Self-Powered Sensing

On‐Body Bioelectronics: Wearable Biofuel Cells for Bioenergy Harvesting and Self‐Powered Biosensing

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