We constructed a record of percent biogenic silica (opal) accumulation at Ocean Drilling Program Site 745B located in the Indian Ocean sector of the Antarctic Zone of the Southern Ocean. The record spans the majority of the early Pleistocene (1.1–2.6 Ma). Orbital‐scale sampling affords a look at the relative importance of obliquity versus precession variability through a time interval that is characterized by obliquity pacing in early Pleistocene δ18O records. Variations in the site's magnetic susceptibility record closely resemble those in the benthic foraminiferal δ18O stack (Lisiecki & Raymo, 2005, https://doi.org/10.1029/2004pa001071) and provide orbital‐scale age control. Between 1.1 and 1.8 Ma, obliquity‐related 41 kyr spectral peaks dominate with relatively little power at precession periods (23–19 kyr) in all records. Between 1.8 and 2.6 Ma, only the δ18O and magnetic susceptibility data display a distinct 41 kyr peak, while the opal lacks spectral power at any of the orbital periodicities. The lack of more pronounced precession‐scale variations in the two proxy records is consistent with observations in foraminiferal δ18O records. A low or absent response to precession in these records appears to be due to environmental control. Lack of orbital forcing in the opal record before 1.8 Ma may reflect both a more southerly location of the polar frontal zone with respect to the site, and thus the site's position outside the region of wind‐driven upwelling, and/or upwelling waters undersaturated with respect to silica prior to the establishment of the opal belt at about 2 Ma.