This paper presents a level-crossing successive-approximation-register (LC-SAR) hybrid analog-to-digital converter (ADC) that combines an LC ADC with an SAR ADC, which may be used for Internet of Things (IoT) random sparse event scenarios. The sampling frequency of a traditional LC ADC is usually proportional to the maximum instantaneous rate of change of the input signal; therefore, a higher input signal frequency inevitably leads to higher system power consumption. However, the proposed hybrid ADC uses the input level difference between the two moments before and after level-crossing detection, thereby ensuring a higher conversion precision and lower power consumption, even at higher input signal frequencies. Compared with traditional LC ADC or SAR ADC, the proposed hybrid ADC combines the ultralow-power advantage of LC ADC with the high-precision advantage of SAR ADC in converting IoT data with sparse characteristics such as ECG, EEG, and brain potential. The LC-SAR hybrid ADC is designed with a 0.18 μm CMOS process and consumes 4.34 μW at a 1.8 V supply voltage, achieving an SNDR of 67.41 dB and a bandwidth of 20 kHz. The spectrum analysis result was 10.85 ENOB when the input sinusoidal signal was 14.975 kHz. When inputted with an ECG signal, the system power consumption was as low as 0.49 μW. Furthermore, the proposed hybrid ADC obtained a good figure of merit, with FoMw and FoMs reaching 58.8 fJ/conv.steps and 164 dB, respectively. Compared to a conventional uniform sampling ADC, approximately 80% of the power savings and an 8x compression ratio can be achieved in physiological signal acquisition applications.