A 27-kg Giant Ovarian Mucinous Cystadenoma in a 72-Year-Old Postmenopausal Patient: A Case Report

Abstract

Patient: Female, 72Final Diagnosis: Benign ovarian mucinous cystadenomaSymptoms: Difficulty breathing and ambulation • heartburn • reflux • early satiety • nauseaMedication: —Clinical Procedure: Total abdominal hysterectomy along with bilateral salpingo-oophorectomySpecialty: Obstetrics and GynecologyObjective:Rare diseaseBackground:Mucinous cystadenoma is a benign cystic ovarian tumor arising from the surface epithelium of the ovary; it usually presents with vague, unspecific abdominal symptoms. If not detected early, they have the potential to grow to a substantial size and can present with huge abdominal distention leading to various compression symptoms. Mucinous cystadenomas most commonly occur in the third to sixth decades of life, and rarely occur in extremes of age. The reported incidence of giant ovarian cystadenoma in postmenopausal women is low or relatively unknown due to widespread use of ultrasound and other radiological imaging modalities these days. Here, we report a case of giant mucinous cystadenoma in a 72-year-old postmenopausal woman with multiple comorbidities.Case Report:We present the case of a 72-year-old postmenopausal high-risk patient who presented with a huge abdominal distention which started gradually 1 year before. Abdominopelvic ultrasound showed a left giant multiloculated abdominal cyst. An intact 27-kg ovarian cyst was removed, and a total abdominal hysterectomy (TAH) along with bilateral salpingo-oophorectomy (BSO) was performed. The final histopathological report showed a benign ovarian mucinous cystadenoma.Conclusions:Mucinous cystadenoma is a benign neoplastic disease that can reach a massive size. They are rare in the post-menopausal age group, but when they do occur, they pose a diagnostic and therapeutic challenge. This case report highlights the importance of early detection and management of adnexal masses in postmenopausal high-risk patients to decrease preoperative and postoperative complications and improve quality of life.

A Rare Case of Massive Ovarian Mucinous Cystadenoma With Postmenopausal Bleeding

“…There are different subtypes and tumor cell origins that lead to ovarian neoplasms. These include surface epithelium, germ cell, or sex cord-stromal tissue [6]. The majority of the diagnosed ovarian neoplasms are benign, and 95% of all gynecological malignancies are due to epithelial cells.…”

“…Cancer antigen 125 (CA-125) is an important tumor marker that helps differentiate between benign and malignant ovarian masses [1]. Hence, it is ideal to offer early screening to high-risk women with a family history of ovarian cancer using the tumor marker CA-125 and the transvaginal US that can aid in early diagnosis of this benign adenoma [6]. Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations occur inside the RAS family of G proteins, which signal cell division; such changes promote cell development and are altogether expanded in mucinous ovarian tumors, including mucinous cystadenomas and adenocarcinomas [4].…”

Diagnosis and management of benign ovarian tumors at the Ignace Deen Maternity Hospital of Conakry University Hospital in Guinea

“…17 Akhras et al, reported the case of a 72-year-old woman who underwent a mucinous cystadenoma weighing 27 kg. 18 The patients' stay in the ward after the procedure was relatively brief, with an average stay of 3.2 days. Steady patients with reverted transit were released on the second or third postoperative day.…”

Huge Abdominal Mass in a Young Unmarried Lady - A Social and Psychotherapeutic Challenge

“…. Although ovarian tumours are relatively common [3], huge ovarian tumours are rare. This is in part due to the improvement of medical imaging and hence earlier detection of these tumours [4].…”