A 42-year-old female with eating disorder complicated by hypothyroidism due to excess iodine ingestion and refeeding syndrome

Hiwa, Ryosuke; Sada, Ryuichi; Azuma, Teruhisa; Ishimaru, Hiroyasu; Hatta, Kazuhiro; Kohri, Yoshiaki

doi:10.12936/tenrikiyo.12-006

Cited by 1 publication

(1 citation statement)

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“…We searched "Igakuchuozasshi" (Japan Medical Abstracts Society) and PubMed for case reports that are similar to the present case. We found five case reports of iodine-induced hypothyroidism associated with anorexia nervosa [14,15,[17][18][19][20] and six case reports of hypothyroidism caused by iodine-containing ointments (Table 2) [2][3][4][5][6][7]. However, to the best of our knowledge, no previous paper has reported a case of hypothyroidism caused by an iodine-containing ointment in a patient with anorexia nervosa.…”

Section: Discussionmentioning

confidence: 99%

Iodine-containing ointment–induced hypothyroidism in a patient with anorexia nervosa and sacral decubitus ulcer: a case report with literature review

et al. 2022

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We present a case of a 58-year-old woman with anorexia nervosa and a sacral decubitus ulcer who developed hypothyroidism because of an iodine-containing ointment. Considering the absence of autoimmune thyroid diseases, the development of hypothyroidism after the use of an iodine-containing ointment, and the recovery of thyroid function after the discontinuation of the ointment, we presumed that her hypothyroidism was induced by the iodine-containing ointment. Although the hypothyroidism improved after discontinuing the iodine-containing ointment, she developed aspiration pneumonia and required long-term hospitalization. Many patients with autoimmune thyroid diseases develop hypothyroidism after excessive iodine intake. However, anorexia nervosa may have exacerbated the iodine-induced hypothyroidism in our patient. To the best of our knowledge, no previous study has reported a case of hypothyroidism caused by iodine-containing ointment in a patient with anorexia nervosa. Hence, physicians must pay careful attention to a patient's background factors to ensure the early diagnosis of hypothyroidism due to iodine-containing ointments.

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