A 66-Year-Old Woman With Fever, Cough, and a Tongue Lesion

Gandhi, Viral; Singh, Amteshwar; Woods, Gail L.; Epelbaum, Oleg

doi:10.1378/chest.14-1858

Cited by 8 publications

(8 citation statements)

References 28 publications

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“…24 When diagnosed accurately treatment of blastomycosis is likely curative and if treatment failure does occur it is usually due to severe pulmonary involvement early in the course of therapy. 25 This is similar to what has been reported in dogs. 26 Relapse of disease was not reported in people other than a known noncompliant patient in which manifestation of primary lung disease spread to the sinuses.…”

Section: Discussionsupporting

confidence: 90%

“…For severe cases, the IDSA recommends induction with AmB [amphotericin B] for one to two weeks or until there is clinical evidence of improvement, followed by maintenance therapy with itraconazole for six to 12 months. 19,24,25 In people there is a high rate of complete resolution with compliant therapy, but there are no known published guidelines on follow up examination intervals. 24 When diagnosed accurately treatment of blastomycosis is likely curative and if treatment failure does occur it is usually due to severe pulmonary involvement early in the course of therapy.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Mandibular Blastomycosis in a 5-Year-Old Dog

Washington

Paulman²,

Stapleton

2022

J Vet Dent

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A case of localized oral mandibular blastomycosis is described in a five-year-old dog. Complete resolution of clinical signs and oral radiographic changes were seen following itraconazole therapy at 5 mg/kg/day for four and a half months. The patient remained free of Blastomyces at the one year follow up based on the Mira Vista Blastomyces urine antigen test by EIA (Enzyme Immunoassay)a. A literature review of localized blastomycosis cases in humans and dogs was performed, available diagnostic tests evaluated, and treatment comparisons made.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionmentioning

confidence: 99%

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Mandibular Blastomycosis in a 5-Year-Old Dog

Washington

Paulman²,

Stapleton

2022

J Vet Dent

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“…Despite growing awareness that Blastomyces spp is a relevant pathogen in NYS and sporadic encounters with it even in NYC and its environs [ [3] , [4] , [5] ], to our knowledge this is the first published case of blastomycosis in a SOT recipient from a transplant center located in NYS. Authors from Illinois, an endemic area, have previously reported ARDS in an OLT recipient who, like our patient, was placed on V–V ECMO and did not survive [ 6 ].…”

Section: Discussionmentioning

confidence: 99%

Fatal acute respiratory distress syndrome caused by blastomycosis after recent orthotopic liver transplantation in a non-endemic area

Sogawa

Misawa

Bodin

et al. 2022

Medical Mycology Case Reports

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“…According to them, a 52 years old man with diabetes shows adrenal involvement in histoplasmosis [26]. Additionally, one case has reported in a Nepalese migrant to the USA with evidence of infection being acquired in Nepal by Gandi et al, in 2015 [27]. Nepal and India have an open border, and a large number of Nepalese migrants is directly dependent on Indian economic and cultural aspects such as employment, education, social relationship, and trade among other elements.…”

Section: Epidemiologymentioning

confidence: 99%

Infectious sources of Histoplasmosis and molecular techniques for its identification

Bhandari

Rayamajhee²,

Dhungel

et al. 2019

Nepal J Biotechnol

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Histoplasmosis, a fungal infection caused by Histoplasma capsulatum (H. capsulatum), acquired from contaminated soil with droppings of chicken or birds and found to be distributed in many parts of the world. The prevalence of histoplasmosis has not well studied in Nepal. The common symptoms of acute and epidemic histoplasmosis include high fever, cough, and asthenia and weight loss. Most of the infections associated with histoplasmosis are asymptomatic. People with compromised immune systems such as HIV/AIDS (PLWHA), cancer, and organ transplant recipients are at risk of developing this disease. In this review, we have summarised the current status of histoplasmosis in Nepal and molecular techniques available for its identification. To date, the significant outbreak is not reported in Nepal, but the risk of infection for the vulnerable population cannot be undermined. Appropriate preventive measures and treatment on time can reduce the burden of this fungal disease. Further, this review is also focused on molecular identification of H. capsulatum. Hence, careful considerations by concerned stakeholders for national surveillance programs and the treatment of patients on time after proper diagnosis is highly recommended.

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A 66-Year-Old Woman With Fever, Cough, and a Tongue Lesion

Cited by 8 publications

References 28 publications

Mandibular Blastomycosis in a 5-Year-Old Dog

Mandibular Blastomycosis in a 5-Year-Old Dog

Fatal acute respiratory distress syndrome caused by blastomycosis after recent orthotopic liver transplantation in a non-endemic area

Infectious sources of Histoplasmosis and molecular techniques for its identification

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