A Battery Method to Enhance the Degradation of Iron Stent and Regulating the Effect on Living Cells

Abstract

Iron is a promising material for cardiovascular stent applications, however, the low biodegradation rate presents a challenge. Here, a dynamic method to improve the degradation rate of iron and simultaneously deliver electrical energy that could potentially inhibit cell proliferation on the device is reported. It is realized by pairing iron with a biocompatible hydrogel cathode in a cell culture media‐based electrolyte forming an iron‐air battery. This system does not show cytotoxicity to human adipose‐stem cells over a period of 21 days but inhibits cell proliferation. The combination of enhanced iron degradation and inhibited cell proliferation by this dynamic method suggests it might be an approach for restenosis inhibition of biodegradable stents.

Employing a chelating agent as electrolyte additive with synergistic effects yields highly reversible zinc metal anodes

“…43,53 Generally, there are two forms of the solvation structure of Zn ]). 6,31 The primary solvent shell (PSS, Zn 2+ -(H 2 O) 6 ) (Fig. 2b) formed owing to the electrostatic attraction of Zn to H 2 O molecules displays obvious electrostatic repulsion, which is an important reason hindering the transportation of zinc ions.…”

“…Electrolyte additives play a significant role in both the solvation structure of Zn 2+ and Zn anode/electrolyte interfacial interaction modulation. For example, ionic additives with low reduction potentials, such as K + , 31 Li + , 32 Na + , 33 La 3+ , 34 Ce 3+ , 35 and Al 3+ , 36 could adsorb on the tip of Zn anode surface to form an electrostatic shield shell, thus achieving uniform deposition of zinc ions. Unfortunately, the heavy metal salt additives will not only increase the cost of battery manufacture, but also cause serious environmental pollution issues, drastically diminishing the advantages of aqueous ZIBs.…”

Progress in the preparation of Prussian blue-based nanomaterials for biomedical applications

“…[155][156][157] Gels are often used in wound dressings, vascular stents, tissue adhesion, and cardiac patches in the biomedical field. [158][159][160][161] Injectable hydrogels are also used as carriers to load drugs for sustained and controlled drug release, targeted release, or loaded with nanoparticles for diagnosis and treatment of tumors. While microgels and nanogels are polymers with a size in the range of 1-1000 nm, and are cross-linked and polymerized within the molecule, they have wider applications in diagnostic analysis and regulation of enzyme activity due to their smaller size.…”

Massively Reconstructing Hydrogen Bonding Network and Coordination Structure Enabled by a Natural Multifunctional Co‐Solvent for Practical Aqueous Zn‐Ion Batteries

“…[ 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 ] Among them, aqueous Zn‐ion batteries (AZIBs) are considered as one of the most promising energy storage systems, owing to their high safety, environmental friendliness, and abundant zinc resources. [ 13 , 14 , 15 ] In addition, the Zn anode has a low redox potential (0.762 V vs. SHE) and a high theoretical volumetric capacity (5855 mAh cm −3 ). [ 16 , 17 ] Despite these advantages, the development of AZIBs is still severely hindered by the uneven Zn deposition and the active H 2 O in the electrolyte.…”