A benign parathyroid cyst presenting with hoarse voice

Sen, Purnendu; Flower, Norman; Papesch, Michael; Davis, Albert D.; Spedding, Anne V.

doi:10.1258/0022215001904923

Cited by 27 publications

(23 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Mediastinal PC usually represent large structures (≥4 cm). [14][15][16] Additionally, unusual symptoms, such as vocal cord paralysis due to local compression on recurrent laryngeal nerve, [17][18][19] respiratory failure and jugular vein thrombosis due to a large mediastinal nonfunctioning PC, have been described. 20 Nonfunctioning PC can also be located inside the thyroid where they are discovered as an incidental finding after NA during the evaluation of a multinodular goiter or a solitary thyroid nodule.…”

Section: General Commentsmentioning

confidence: 99%

Diagnostic and therapeutic review of cystic parathyroid lesions

Pontikides¹,

Karras²,

Kaprara³

et al. 2012

View full text Add to dashboard Cite

BAcKGrOUND: Parathyroid cysts (Pc) are uncommon entities in routine clinical practice. The vast majority are nonfunctioning and are commonly present as asymptomatic nodular cervical lesions. Pc should be considered in the differential diagnosis of an asymptomatic neck mass. Large Pc can manifest with compressive symptoms of the surrounding tissues. OBJEcTIVE: The aim of this study is to describe nine new cases of Pc and review the current literature regarding the clinical presentation, the aetiopathology, the diagnostic procedures, as well as the therapeutic approaches for this relatively rare clinical entity. METHODs-PATIENTs: We present nine new patients (7 females and 2 males) diagnosed with Pc, which in three were ectopic. The diagnosis of Pc was based on the elevated levels of PTH in the cysts fluid. six of the patients had nonfunctioning parathyroid lesions, while the other three had functioning ones. Patients with functioning Pc had elevated serum calcium and PTH levels. Five out of nine of the cases had no symptoms, while two patients had compressive symptoms and the other two had signs and symptoms of hypercalcaemia. Needle aspiration (NA) was performed in five out of six patients with nonfunctioning Pc. surgery was the treatment in all three patients with functioning Pc. rEsULTs: remission after NA was achieved in four out of five patients with non-functioning Pc (follow-up time: 17.7±2.3 months). In two of them, two and three aspirations were needed. One patient with nonfunctioning Pc submitted to surgery with no previous NA. Patients with functioning Pc maintained remission after surgery (mean follow-up time: 22.1±2.9 months). In one of them, a second surgery was performed due to the co-existence of an ectopic parathyroid adenoma. cONcLUsIONs: The diagnosis of a Pc can be established by finding high levels of PTH in the fluid collected by the aspiration of the cyst. PTH and ca levels in the serum can differentiate functioning from nonfunctioning Pc. The treatment of HORMONES 2012, 11(4):410-418 Review

show abstract

Section: General Commentsmentioning

confidence: 99%

Diagnostic and therapeutic review of cystic parathyroid lesions

Pontikides¹,

Karras²,

Kaprara³

et al. 2012

View full text Add to dashboard Cite

show abstract

“…The cyst may be adhered to the thyroid tissue, but it is easily separated from it 1,5 . Treatment for nonfunctioning cysts without complications may be US-guided aspiration, once there are no reports of malignancy 14 . Sclerotherapic substances may be introduced even though they are not universally accepted owing to complications, such as neurotoxicity or recurrent laryngeal nerve paralysis.…”

Section: Discussionmentioning

confidence: 99%

“…Macroscopic observation of parathyroid cysts intraoperatively is of a solitary unilocular cyst adhered to the thyroid tissue, but the defined cleavage plan has thin, glossy and clearcontent walls, in the lower portion of the neck. Mediastinum cysts are normally treated with surgery 14 . In many series, including the one by Rosenbrg et al 3 , lobectomy or partial thyroidectomy were advocated in treating parathyroid cysts.…”

Section: Discussionmentioning

confidence: 99%

Cisto de paratireóide: aspectos diagnósticos e tratamento

Silva

Machado

Brito

et al. 2004

Rev. Bras. Otorrinolaringol.

View full text Add to dashboard Cite

Parat hyroid cysts are rare lesions, usually located in the neck and mediastinum in about 10% of the cases, predominantly in women. The majority of the lesions are nonfunctioning; however, functioning cysts are associated with hyperparathyroidism. The diagnosis of parathyroid cyst is difficult, and frequently misdiagnosed as thyroid pathology and the final diagnosis is made during surgery confirmed by histopathological examination. A crystal clear fluid and elevated PTH levels in cyst fluid confirm the diagnosis.

show abstract

“…In total, 15-57% of PCs are functional (5)(6)(7). In addition, the majority of non-functional PC lesions are small in size and are occasionally revealed during imaging procedures or cervical surgery, with only a minority characterized by a large size and compressive symptoms (8). The present study describes the case of a man with a giant non-functional PC extending from the lower neck to the superior mediastinum, and provides a brief discussion regarding the associated literature in order to raise awareness of this diagnosis.…”

Section: Introductionmentioning

confidence: 93%

Giant non-functional parathyroid cyst: A case report

Zhang

Yuan

et al. 2016

Oncology Letters

View full text Add to dashboard Cite

Abstract. Giant parathyroid cysts (PCs) are a rare entity and possess a benign clinical course. PCs may be functional or non-functional, depending on the ability of the cyst to secrete parathyroid hormone (PTH). The present study reports a rare case of a giant PC in a 56-year-old male who presented to the Affiliated Tumor Hospital, Zhengzhou University (Zhengzhou, Henan, China) with a 10-month history of exertional dyspnea, associated with mild dysphagia that had persisted for 3 months. The present study reviews the clinical situation, laboratory examination, radiographic findings, treatment and prognosis of the patient, and provides a brief discussion regarding the associated literature. Giant PCs may manifest with compressive symptoms of the surrounding tissues. The diagnosis of a giant PC is based on increased levels of PTH in the fluid collected during the aspiration of the cyst. Management by surgical excision is recommended for giant PCs that cause local cervical symptoms.

show abstract

A benign parathyroid cyst presenting with hoarse voice

Cited by 27 publications

References 5 publications

Diagnostic and therapeutic review of cystic parathyroid lesions

Diagnostic and therapeutic review of cystic parathyroid lesions

Cisto de paratireóide: aspectos diagnósticos e tratamento

Giant non-functional parathyroid cyst: A case report

Contact Info

Product

Resources

About