A Biologically Inspired Networking Model for Wireless Sensor Networks. (December 2009) Charalambos Charalambous, B.S., The University of Arizona Chair of Advisory Committee: Dr. Shuguang Cui Wireless sensor networks (WSNs) have emerged in strategic applications such as target detection, localization, and tracking in battlefields, where the large-scale nature renders centralized control prohibitive. In addition, the finite batteries in sensor nodes demand energy-aware network control. In this thesis, we propose an energyefficient topology management model inspired by biological inter-cellular signaling schemes. The model allows sensor nodes to cluster around imminent targets in a purely distributed and autonomous fashion. In particular, nodes in the target vicinity collaborate to form clusters based on their relative observation quality values. Subsequently, the clustered sensor nodes compete based on their energy levels until some of them gain active status while the rest remain idle, again according to a distributed algorithm based on biological processes. A final phase of the model has the active cluster members compete until one of them becomes the clusterhead. We examine the behavior of such a model in both finite-size and infinite-size networks. Specifically, we show that the proposed model is inherently stable and achieves superior energy efficiency against reference protocols for networks of finite size. Furthermore, we discuss the behavior of the model in the asymptotic case when the number of nodes goes to infinity. In this setting, we study the average number of cluster members. iv To my parents, Andreas and Ifigenia Charalambous v ACKNOWLEDGMENTS I have the best of memories from my graduate studies at Texas A&M University. I have made friends and acquaintances from every corner of the world, all walks of life, and different academic backgrounds, all of whom have been influential in my life one way or another.