2023
DOI: 10.12688/f1000research.139116.1
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A Bioconductor workflow for processing, evaluating, and interpreting expression proteomics data

Charlotte Hutchings,
Charlotte S. Dawson,
Thomas Krueger
et al.

Abstract: Background: Expression proteomics involves the global evaluation of protein abundances within a system. In turn, differential expression analysis can be used to investigate changes in protein abundance upon perturbation to such a system. Methods: Here, we provide a workflow for the processing, analysis and interpretation of quantitative mass spectrometry-based expression proteomics data. This workflow utilizes open-source R software packages from the Bioconductor project and guides users end-to-end and step-by… Show more

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