A Birth Cohort Analysis of the Incidence of Papillary Thyroid Cancer in the United States, 1973–2004

Zhu, Cairong; Zheng, Tongzhang; Kilfoy, Briseis A.; Han, Xuesong; Ma, Shuangge; Ba, Yue; Bai, Yana; Wang, Rong; Zhu, Yong; Zhang, Yawei

doi:10.1089/thy.2008.0342

Cited by 137 publications

(129 citation statements)

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“…In our study, the thyroid cancers accounted for 1.1% of all cancers; this finding is consistent with the literature data where the prevalence is usually around 1% (Davies et al, 2006). The evolution of the incidence of thyroid cancers can vary within a country, due to the occurrence of a particular epidemiological context or a change in diagnostic performance (Cotterill et al, 2001;Zhu et al, 2009). In the first case, it's necessary to highlight the influence of nuclear radiation.…”

Section: Discussionsupporting

confidence: 91%

Descriptive Epidemiology of Thyroid Cancers in Togo

Darré

Amana²,

Pegbessou³

et al. 2015

Asian Pacific Journal of Cancer Prevention

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Background: The purpose of this study was to provide epidemiological and histological data of thyroid cancers in Togo. Materials and Methods: This was a retrospective cross-sectional study of cases of thyroid cancers diagnosed from 2000 to 2014 (15 years) at the pathology laboratory of the Sylvanus Olympio Teaching Hospital of Lomé. All cases of review of a thyroid sample (biopsies, surgical specimens) were collected from the data records of that laboratory. Results: Thyroid cancers represented 1.1% (7930cases) of all cancers registered during the study period. Mean age was 45.4±0.3 years and the proportion of females was 78.3%. We identified 92.4% carcinomas and 7.6% lymphomas. Carcinomas were well differentiated in 80 cases and were dominated by the papillary type (47 cases). Metastasis was observed in 13% of patients. The pTNM classification evaluated in 18 cases showed a predominance of grade I (13 cases). Lymphomas were dominated by lymphoma diffuse large B-cell (5 cases). Conclusions: This study is the first global standard for thyroid cancer pathology in Togo. The high frequency of follicular form suggests an unrecognized iodine deficiency. The improvement of the technical platform of the LAP (immunohistochemistry) will increase the diagnosis of rare forms of thyroid cancer.

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Section: Discussionsupporting

confidence: 91%

Descriptive Epidemiology of Thyroid Cancers in Togo

Darré

Amana²,

Pegbessou³

et al. 2015

Asian Pacific Journal of Cancer Prevention

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“…A recent ecologic study using the Surveillance, Epidemiology and End Results (SEER) data indicated that higher levels of healthcare access are associated with higher papillary thyroid cancer rates, which provided supportive evidence for the overdiagnosis of thyroid cancer (3). However, other studies offered divergent opinions (4,5). The study based on the Department of Defense's Automated Central Tumor Registry found that the age-adjusted incidence rate of thyroid cancer in the military was significantly higher than the general population, and the rates varied by military service branch, suggesting that heightened medical surveillance does not appear to explain the temporal increase in thyroid cancer incidence fully (4).…”

Section: Introductionmentioning

confidence: 99%

The Epidemic of Thyroid Cancer in the United States: The Role of Endocrinologists and Ultrasounds

Udelsman

Zhang

2014

Thyroid

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Background: The incidence of thyroid cancer has increased at an alarming rate in both men and women in the United States. The etiology of this epidemic is unclear. We tested the hypothesis that a significant component of this epidemic is due to increased detection of occult disease. We examined whether the density of endocrinologists and general surgeons as well as employment of cervical ultrasonography were factors associated with this epidemic. Methods: Thyroid cancer incidence rates by states were obtained from the United States Cancer Statistics 1999-2009 reported by the National Program of Cancer Registries. The densities of endocrinologists and general surgeons and the employment of cervical ultrasonography were calculated on a statewide basis and correlated with the incidence of thyroid cancer. Results: Age-standardized incidence rates of thyroid cancer have increased in every state in the United States. Significant regional variations were noted, with the highest incidence rates in the northeast and the lowest in the south. The incidence rates were significantly correlated with the density of endocrinologists (r = 0.58, p < 0.0001 for males; r = 0.44, p = 0.0031 for females) and the employment of cervical ultrasonography (r = 0.40, p = 0.0091 for males; r = 0.36, p = 0.0197 for females). Both the density of endocrinologists and general surgeons and employment of cervical ultrasonography could explain 57% of the variability in state-level incidence for males and 49% for females. Conclusions: These data offer evidence to suggest that the epidemic of thyroid cancer is due to increased detection of a reservoir of previously occult disease. The increased detection of thyroid cancer results in therapeutic interventions including surgery and radioactive thyroid treatment that may be of limited benefit.

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“…A number of factors are taken into consideration for the geographical and biographical differences in the different stages. In addition to genetic factors [14], nutritional reasons, among others, play a role [15]. In this context, there is an association of FTC with a lack of dietary iodine [15].…”

mentioning

confidence: 99%

“…In addition to genetic factors [14], nutritional reasons, among others, play a role [15]. In this context, there is an association of FTC with a lack of dietary iodine [15]. In a recently published study of 4955 patients and 7348 assessed thyroid nodules, it was shown that there is not a linear association of increasing nodule size and malignancy risk [16].…”

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confidence: 99%