Taking advantages of both the oxidation property of hypochlorite and different coordination properties of Cu and Cu ions, we developed a new fluorescent probe for hypochlorite anion, namely, compound C1. In the presence of ClO, the sensing system displayed extraordinary fluorescence quenching, which was beneficial to the production of a high signal output during detection process. By virtue of its special oxidation property, the probe displayed high selectivity for ClO over other anions. Moreover, this novel sensing system could be used for the analysis of ClO levels in tap water and potentially in environmental samples.