A brief cognitive test battery to differentiate Alzheimer's disease and frontotemporal dementia

Mathuranath, P. S.; Nestor, Peter J.; Berrios, G. E.; Rakowicz, Wojtek; Hodges, J. R.

doi:10.1212/wnl.55.11.1613

Cited by 140 publications

(207 citation statements)

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“…All participants were evaluated with an extensive neuropsychological battery. Data for this study were obtained from the following tests: the IFS, the Addenbrooke's Cognitive Examination (ACE; Mathuranath, Nestor, Berrios, Rakowicz, & Hodges, 2000 ) which also incorporates the MMSE (Folstein, Folstein, & McHugh, 1975 ), and classical executive measures, including the verbal phonological fl uency (Lezak, 1995 ), Trail Making Test -Part B (Partington & Leiter, 1949 ), and the WCST (Nelson, 1976 ). IFS content, instructions, and scoring for each of the subtests are included as an appendix to this article.…”

Section: Methodsmentioning

confidence: 99%

INECO Frontal Screening (IFS): A brief, sensitive, and specific tool to assess executive functions in dementia – ERRATUM

Torralva¹,

Roca²,

Gleichgerrcht³

et al. 2009

J Int Neuropsychol Soc

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Section: Methodsmentioning

confidence: 99%

INECO Frontal Screening (IFS): A brief, sensitive, and specific tool to assess executive functions in dementia – ERRATUM

Torralva¹,

Roca²,

Gleichgerrcht³

et al. 2009

J Int Neuropsychol Soc

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“…The Australian version of the Revised Addenbrooke's Cognitive Examination (Mathuranath et al, 2000) was used to quantify general cognitive status. This measure assesses six cognitive domains; orientation, attention, memory, verbal fluency, language, and visuospatial ability.…”

Section: Cognitive Ability and Psychological Wellbeingmentioning

confidence: 99%

“…This measure assesses six cognitive domains; orientation, attention, memory, verbal fluency, language, and visuospatial ability. It has been shown to have high reliability, construct validity, and sensitivity to the presence of dementia (Mathuranath et al, 2000). Scores range from 0 to 100, with a score of 83 or less (out of 100) suggestive of potential cognitive deficits.…”

Section: Cognitive Ability and Psychological Wellbeingmentioning

confidence: 99%

Cognitive disinhibition and socioemotional functioning in Alzheimer's disease

Nash

McDonald

Martin

et al. 2007

J Int Neuropsychol Soc

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Individuals with Alzheimer's disease (AD) experience difficulties with socioemotional functioning, and it has been proposed that cognitive disinhibition may be one potential mechanism that contributes to difficulties in this area. To test this possibility, twenty individuals with AD and 20 demographically matched controls were administered self-report measures of depression, emotion regulation and empathy, in addition to a behavioral measure that has proven to be very sensitive to inhibitory failures (the Hayling Sentence Completion Test). Relative to controls AD participants exhibited increased inhibitory failures on the Hayling, and self-reported significantly reduced cognitive empathy, but did not differ with respect to affective empathy, depression or perceived capacity for emotion regulation. Controlling for general cognitive status, in the AD (but not the control) group, reduced cognitive inhibition was associated with lower levels of depression. The theoretical and practical implications of these results are discussed. (JINS, 2007(JINS, , 13, 1060(JINS, -1064

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“…We recruited ten patients with amnestic mild cognitive impairment (MCI) from the Edinburgh Neuropsychological Assessment Service for Older People and ten healthy elderly control subjects over the age of 59 from amongst friends and spouses of patients matched for age, years of education, pre-morbid IQ and sex.. (Mathuranath, et al, 2000), and the Geriatric Depression Scale (Yesavage, 1988). They underwent medical and psychiatric screening (including blood screen), as well as neuroimaging (x-ray computed tomography) to exclude vascular or other brain lesions.…”

Section: Participantsmentioning

confidence: 99%

“…The maximum regression coefficient with Addenbrooke's Cognitive Examination total score (Mathuranath, et al, 2000;see Figure 3a) extended from the left supramarginal gyrus [-46, -42, 32] (Rey, 1941; see Figure 3c) was found in right parahippocampal gyrus ([34, -30, -14], Z=3.58, p<0.001, uncorrected; cluster-level 0.29 cm 3 , p<0.1, uncorrected).…”

Section: Regression With Cognitive Impairmentmentioning

confidence: 99%

5-123I-A-85380 binding to the α4β2-nicotinic receptor in mild cognitive impairment

Terriere

Dempsey

Herrmann

et al. 2010

Neurobiology of Aging

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Treatments currently licensed for Alzheimer's dementia target cholinergic brain systems. In vivo nicotinic receptor binding may provide an early marker of illness and treatment suitability. In this pilot, we examined nine patients with amnestic mild cognitive impairment (MCI) and ten age and education matched healthy volunteers with high resolution SPECT and the nicotinic receptor ligand 123I-5-IA-85380. Uptake data were analysed using voxel-based techniques for group comparisons and regression analyses with cognitive impairment as covariates. MCI patients had discrete reductions in uptake in medial temporal cortex.Correlations with cognitive impairment were found in left temporo-parietal areas (Addenbrooke's Cognitive Examination) and bilateral temporo-limbic areas (Reye Auditory Verbal Learning Test), and right parahippocampal gyrus (Reye Complex Figure Test)

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A brief cognitive test battery to differentiate Alzheimer's disease and frontotemporal dementia

Cited by 140 publications

References 0 publications

INECO Frontal Screening (IFS): A brief, sensitive, and specific tool to assess executive functions in dementia – ERRATUM

INECO Frontal Screening (IFS): A brief, sensitive, and specific tool to assess executive functions in dementia – ERRATUM

Cognitive disinhibition and socioemotional functioning in Alzheimer's disease

5-123I-A-85380 binding to the α4β2-nicotinic receptor in mild cognitive impairment

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