A “built-up” composite film with synergistic functionalities on Mg–2Zn–1Mn bioresorbable stents improves corrosion control effects and biocompatibility

Dou, Zhenglong; Chen, Shuiling; Wang, Jiacheng; Li, Xia; Maitz, Manfred F.; Tu, Qiufen; Zhang, Wentai; Yang, Zhilu; Huang, Nan

doi:10.1016/j.bioactmat.2023.02.004

Cited by 6 publications

(4 citation statements)

References 79 publications

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“…To replicate in vivo conditions, we employed tris/HCl-buffered SBF as the corrosion medium, allowing the assessment of sample corrosion behaviour in vitro . Once the samples were fixed in the hydrogen collection device, they were submerged in 250 mL of SBF at 37 °C using a fishing line, and the solution was replaced every 48 h. 38 The blank group mirrored the experimental group except for the absence of samples.…”

Section: Methodsmentioning

confidence: 99%

Metal–organic complex coating for enhanced corrosion control and biocompatibility on biodegradable magnesium alloy for orthopaedic implants

Wang,

Dou,

Xia

et al. 2024

J. Mater. Chem. B

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Section: Methodsmentioning

confidence: 99%

Metal–organic complex coating for enhanced corrosion control and biocompatibility on biodegradable magnesium alloy for orthopaedic implants

Wang,

Dou,

Xia

et al. 2024

J. Mater. Chem. B

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“…Prior studies have demonstrated the promise of utilizing PLGA as a surface coating, particularly on Mg or Zn alloys, owing to its commendable attributes including robust biocompatibility, pronounced hydrophobicity, and proficient drug-loading capabilities (Wang et al, 2006;Zhu and Braatz, 2015;Dou et al, 2023). The versatile applications of PLGA coatings have been extensively explored by researchers in various stent domains, including cardiovascular stents (Fang et al, 2021;Dou et al, 2023), ureteral stents (Antonowicz et al, 2021), and gastrointestinal stents (Kwak et al, 2017), among others. Liu et al (2022) designed and tested a groundbreaking Mg-based braided stent coated with PLGA infused with paclitaxel (PTX) to avoid secondary removal by endoscopic procedures and inhibit restenosis of the esophagus (Figure 1).…”

Section: Plgamentioning

confidence: 99%

Comprehensive review of materials, applications, and future innovations in biodegradable esophageal stents

Yang,

Hou

et al. 2023

Front. Bioeng. Biotechnol.

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Esophageal stricture (ES) results from benign and malignant conditions, such as uncontrolled gastroesophageal reflux disease (GERD) and esophageal neoplasms. Upper gastrointestinal endoscopy is the preferred diagnostic approach for ES and its underlying causes. Stent insertion using an endoscope is a prevalent method for alleviating or treating ES. Nevertheless, the widely used self-expandable metal stents (SEMS) and self-expandable plastic stents (SEPS) can result in complications such as migration and restenosis. Furthermore, they necessitate secondary extraction in cases of benign esophageal stricture (BES), rendering them unsatisfactory for clinical requirements. Over the past 3 decades, significant attention has been devoted to biodegradable materials, including synthetic polyester polymers and magnesium-based alloys, owing to their exceptional biocompatibility and biodegradability while addressing the challenges associated with recurring procedures after BES resolves. Novel esophageal stents have been developed and are undergoing experimental and clinical trials. Drug-eluting stents (DES) with drug-loading and drug-releasing capabilities are currently a research focal point, offering more efficient and precise ES treatments. Functional innovations have been investigated to optimize stent performance, including unidirectional drug-release and anti-migration features. Emerging manufacturing technologies such as three-dimensional (3D) printing and new biodegradable materials such as hydrogels have also contributed to the innovation of esophageal stents. The ultimate objective of the research and development of these materials is their clinical application in the treatment of ES and other benign conditions and the palliative treatment of malignant esophageal stricture (MES). This review aimed to offer a comprehensive overview of current biodegradable esophageal stent materials and their applications, highlight current research limitations and innovations, and offer insights into future development priorities and directions.

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“…Recently, various biocompatible and bioresorbable materials, including organic and inorganic materials [4][5][6][7][8], have been utilized to serve as actively functional layers for the fabrication of transient electronic devices/systems. Organic transient electronics have exhibited several advantages, such as the natural flexibility to reduce the mechanical mismatch with soft tissues, the convenience in device fabrications (for example, via printing), though the device performances and their stability should be considered.…”

Section: Introductionmentioning

confidence: 99%

Silicon-based transient electronics: principles, devices and applications

Zhao,

Liu,

Guo

2024

Nanotechnology

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Recent advances in materials science, device designs and advanced fabrication technologies have enabled the rapid development of transient electronics, which represents a class of devices or systems that their functionalities and constitutions can be partially/completely degraded via chemical reaction or physical disintegration over a stable operation. Therefore, numerous potentials, including zero/reduced waste electronics, bioresorbable electronic implants, hardware security, and others, are expected. In particular, transient electronics with biocompatible and bioresorbable properties could completely eliminate the secondary retrieval surgical procedure after their in-body operation, thus offering significant potentials for biomedical applications. In terms of material strategies for the manufacturing of transient electronics, silicon nanomembranes are of great interest because of their good physical/chemical properties, modest mechanical flexibility (depending on their dimensions), robust and outstanding device performances, and state-of-the-art manufacturing technologies. As a result, continuous efforts have been made to develop silicon-based transient electronics, mainly focusing on designing manufacturing strategies, fabricating various devices with different functionalities, investigating degradation or failure mechanisms, and exploring their applications. In this review, we will summarize the recent progresses of silicon-based transient electronics, with an emphasis on the manufacturing of silicon nanomembranes, devices, as well as their applications. After a brief introduction, strategies and basics for utilizing silicon nanomembranes for transient electronics will be discussed. Then, various silicon-based transient electronic devices with different functionalities are described. After that, several examples regarding on the applications, with an emphasis on the biomedical engineering, of silicon-based transient electronics are presented. Finally, summary and perspectives on transient electronics are exhibited.

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A “built-up” composite film with synergistic functionalities on Mg–2Zn–1Mn bioresorbable stents improves corrosion control effects and biocompatibility

Cited by 6 publications

References 79 publications

Metal–organic complex coating for enhanced corrosion control and biocompatibility on biodegradable magnesium alloy for orthopaedic implants

Metal–organic complex coating for enhanced corrosion control and biocompatibility on biodegradable magnesium alloy for orthopaedic implants

Comprehensive review of materials, applications, and future innovations in biodegradable esophageal stents

Silicon-based transient electronics: principles, devices and applications

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