A Cage Compound containing Four Thiophene Rings: Synthesis and Structural Conversion by Desulfurization

Abstract

A novel macrocyclic cage compound with four thiophene rings was synthesized following a one-step procedure and then structurally converted by disulfurization.

One‐step syntheses of macrocyclic compounds: A short review

“…Unfortunately, this synthetic approach is not useful for the preparation of small supercryptands with aliphatic connecting groups because small five-or six-membered rings, such as morpholine or piperazine, will preferentially form. Some aliphatic connecting group-containing supercryptands shown in Scheme 33 have been prepared, but in small yields [95][96][97]. However, reactions of the appropriate starting materials do not always give the desired supercryptands but often lead to other macrocyclic compounds as shown in Scheme 34 [96].…”