e accuracy of the rear-end collision models is crucial for the early warning of potential traffic accident identification, and thus analyzes of the main factors influencing the rear-end collision relevant models is an active topic in the field. e previous studies have tried to determine the single factor influence on the rear-end collision model performance. Less attention was paid to exploit mutual influences on the model performance. To bridge the gap, we proposed an improved vehicle rear-end collision model by integrating varied factors which influence two parameters (i.e., response time and road adhesion coefficient). e two parameters were solved with the integrated weighting and neural network models, respectively. After that we analyzed the relationship between varied factors and the minimum car-following distance. e research findings support both the theoretical and practical guidance for transportation regulations to release more reasonable minimum headway distance to enhance the roadway traffic safety.On the basis of the traditional safety distance model, Kong et al. conducted information acquisition, distance judgment, braking, and other processes for active collision avoidance during vehicle travel. However, the judgment model used is relatively simple [5]. Jiang and Yu established a highway antitailing model based on radial basis function neural network by using traditional algorithms [6]. Nevertheless, the model is mainly applied to highways, and the influencing factors are considered to be single. Jing and Wang explored the influence of multiple vehicles on the driver and established a vehicle-following model considering the traffic state based on the full velocity difference (FVD) model [7]. Nonetheless, the model is too complicated to conduct to practical applications. Xia established a fuzzy inference system based on the characteristics (e.g., driving age, and gender) of the driver to determine the response time of different drivers and proposed an improved version of the safe model [8]. Peng and Sun derived the modified Korteweg-de Vries (mKdV) equation to describe the traffic