Objective. Patient presentations to the emergency department (ED) for alcohol-involved injury represent a growing public health burden, but their characteristics and sequelae remain understudied.This study examined mortality rates among ED patients presenting with alcohol-involved injuries, and assessed how mortality varied by injury intent and other characteristics.Method. This retrospective cohort study used statewide, longitudinally-linked ED patient record and mortality data from California. Participants comprised all residents presenting to a licensed ED in 2009-2012 with a nonfatal injury that involved comorbid diagnosis of alcohol use disorder (AUD; n=261,222; 59.3% male). Injury intent was defined using International Classification of Diseases, 9 th Revision external cause-of-injury codes. Cox regression was used to investigate factors associated with 12-month all-cause mortality rates. Age-, sex-, and race/ethnicity-adjusted standardized mortality ratios (SMRs) were calculated using statewide mortality data.
Results. Most ED injury visits involving an AUD diagnosis were coded as unintentional (75.9%).Following the index ED visit, all-cause mortality among AUD-involved injury patients was 5,205 per 100,000 person-years, five times higher than the demographically matched population (SMR: 5.3; 95% CI: 5.2, 5.4). Adjusted Cox regression models indicated that patients whose index injury was unintentional, and whose AUD was for acute intoxication, had significantly higher mortality. Most deaths among unintentionally-injured patients were from natural causes, while external-cause deaths were relatively more common in the other patient groups.Conclusions. AUD-involved injury presentations to the ED are common and associated with high patient mortality burden, which varies by injury intent. Interventions are needed to reduce excess mortality in these patients.