A Case-Case Comparison ofCampylobacter coliandCampylobacter jejuniInfection: A Tool for Generating Hypotheses

Abstract

Preventing campylobacteriosis depends on a thorough understanding of its epidemiology. We used casecase analysis to compare cases of Campylobacter coli infection with cases of C. jejuni infection, to generate hypotheses for infection from standardized, population-based sentinel surveillance information in England and Wales. Persons with C. coli infection were more likely to have drunk bottled water than were those with C. jejuni infection and, in general, were more likely to have eaten pâté. Important differences in exposures were identified for these two Campylobacter species. Exposures that are a risk for infection for both comparison groups might not be identified or might be underestimated by case-case analysis. Similarly, the magnitude or direction of population risk cannot be assessed accurately. Nevertheless, our findings suggest that case-control studies should be conducted at the species level.

Risk factors for indigenousCampylobacter jejuniandCampylobacter coliinfections in The Netherlands: a case-control study

“…The risk of consumption of the internal organs of animals, e.g. tripe, for C. coli enteritis has been confirmed in a previous study [25]. Swimming was an important risk factor for C. coli infections.…”

Detecção de fatores de virulência em estirpes de Campylobacter spp. isoladas de carcaças de suínos abatidos em frigoríficos

“…para o homem, destacandose a espécie suína para o C. coli e os frangos de corte para o C. jejuni (Lander, 1985;Scarcelli et al, 1998;Gillespie et al, 2002;Calil et al, 2008;Scarcelli et al, 2009), como observado no presente estudo, em que prevaleceu a espécie C. coli em 28/31 estirpes isoladas de Campylobacter spp. (90,3%) em relação ao C. jejuni (9,7% -3/31).…”

Do patients with recurrent episodes of campylobacteriosis differ from those with a single disease event?

“…Regional public health authorities are notified of confirmed cases and selected information is then gathered into surveillance databases. These databases can then be used in epidemiological investigations as sources of information for evaluating individual or environmental risk factors [3,4]. It was recently proposed that acquired immunity to the infection could bias results from risk factor analysis by reducing the risk of developing the disease in areas of high exposure [5].…”