A Case-Control Study About Hematological Profile and Morbidity of Newborns at Birth, Born to Mothers With Hypertension in Pregnancy.

Abstract

Background: Hypertensive disorders of pregnancy complicate about 8% of all gestations. Hypertensive disorders are responsible for significant maternal and perinatal morbidity and mortality.
 AIMS: To determine the hematological parameters and morbidity in neonates born to mothers with gestational hypertension, pre-eclampsia or eclampsia syndrome and in neonates born to normotensive mothers without any maternal complications or medical illness with special reference to platelet count and neutrophil count.
 Methods and Material: The study was a prospective study conducted on neonates born to pregnant women complicated with gestational hypertension, pre-eclampsia or eclampsia syndrome and neonates born to normotensive mothers recruited at Neonatal Intensive Care Unit and Post natal wards who were delivered at Ananta Hospital and AIMS & RC, Rajsamand (Raj.) from October 2018 to September 2019 and the hematological parameters of these babies were studied.
 Results: In our study we observed that the mean value of platelet count were significantly lower in study group compared to control group which was highly Statistical significant (p<0.001). The mean value of PT, aPTT, Bleeding Time and Clotting time were significantly higher in study group, as compared to control group. The statistical analytic differences were highly significant in all parameters i.e. PT, aPTT, Bleeding Time and Clotting time (P<0.001).
 Conclusion: To conclude early hematological screening of babies are recommended to facilitate early detection and management of serious neonatal complications describes above, to decrease morbidity and improved growth, development and survival.
 Keywords: Pre-eclampsia, Eclampsia, Gestational Hypertension, Newborns.