A case of a solitary liver abscess complicated by early sigmoid colon cancer.

Tanizaki, Hiroshi; Kawano, Noriaki; Watanabe, Hidejiro; Tsutsumi, Osamu; Hatate, Kazuhiko; Sugai, Takeshi

doi:10.3919/jjsa.63.449

Cited by 6 publications

(3 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is uncommon for colorectal cancer to present with liver abscess and this is reported to occur in ≤5% of patients (20,21).The incidence of abscess formation due to colorectal cancer is highest in the liver, followed by the lungs, and cases of endocarditis and meningitis have also been reported (8)(9)(10)(11)(12)(13)(14)(15)(16). However, to the best of our knowledge there has only been 1 reported case of early colorectal cancer associated with a liver abscess (1), in addition to 2 cases of multiple abscesses due to colorectal cancer (12,16); therefore, the patient in the present case report is the first to be reported with multiple abscesses caused by early rectal cancer.…”

Section: Discussionmentioning

confidence: 99%

“…Of these five cases, 1 early cancer patient (8) and 3 advanced cancer patients exhibited liver abscesses alone (9,10,13) and 1 advanced cancer patient exhibited multiple systemic abscesses (12). Fever was the main symptom in all cases, with weight loss, malaise and nausea/vomiting also observed (8)(9)(10)12,13). In addition, the case of an advanced colorectal cancer patient exhibiting multiple systemic abscesses without any liver abscesses has also been reported (16).…”

Section: Introductionmentioning

confidence: 98%

“…The incidence of postoperative local recurrence in the pelvic cavity is low (5)(6)(7). However, it is not uncommon for colon cancer to cause an abscess in a distant organ (8)(9)(10)(11)(12)(13)(14)(15)(16). Regarding the pathogenesis of systemic abscesses associated with colorectal cancer, small abscesses may form around the tumor or bacterial invasion may occur secondary to damage to the intestinal wall, which is followed by hematogenous spread (13).…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Early rectal cancer accompanied by multiple systemic abscesses: A case report

et al. 2015

View full text Add to dashboard Cite

Abstract.A 70-year-old man undergoing treatment for diabetes presented with a cough and pyrexia that has lasted one week. Laboratory tests demonstrated evidence of inflammation. The patient was hospitalized and antibiotic treatment was initiated, but the condition of the patient did not improve. After 2 weeks, computerized tomography scanning demonstrated the presence of multiple small nodules in the lungs and a liver abscess. The patient also developed neck pain and numbness of the upper extremities and was then transferred to Tokai University Hachioji Hospital (Tokyo, Japan). Percutaneous transhepatic drainage (PTD) of the liver abscess was performed and antibiotic treatment was initiated. Detailed examination revealed there was pyogenic spondylitis of the cervical spine, therefore abscess drainage and an anterior cervical spinal fusion were performed. Culture of each lesion resulted in Klebsiella pneumoniae growth. While continuing antibiotic treatment and rehabilitation, the gastrointestinal tract was investigated and evidence of early rectal cancer was observed. The pulmonary nodules disappeared during treatment, indicating that these were multiple lung abscesses. Four weeks following abscess drainage and anterior cervical spinal fusion, lower anterior resection was performed. The present case report describes a patient who developed multiple abscesses associated with early rectal cancer and discusses the case with reference to the literature. IntroductionAt present, the global incidence of colorectal cancer is increasing, which is considered to be a result of westernization of the diet and obesity (1-4). The main symptoms are rectal bleeding with or without progressive anemia and weight loss. The recommended treatment for stage I colorectal cancer is surgical resection combined with lymph node dissection (5).The 5-year survival rate of patients following resection of stage I colorectal cancer is 90-95%, with postoperative distant metastasis/recurrence occuring in 5-10% of patients (5). The incidence of postoperative local recurrence in the pelvic cavity is low (5-7). However, it is not uncommon for colon cancer to cause an abscess in a distant organ (8-16). Regarding the pathogenesis of systemic abscesses associated with colorectal cancer, small abscesses may form around the tumor or bacterial invasion may occur secondary to damage to the intestinal wall, which is followed by hematogenous spread (13). The development of abscesses may be promoted by the impaired immunity of tumor-bearing patients and associated diseases, such as diabetes, may also affect immunity (12,13). In the literature, five cases of colorectal cancer in which liver abscesses were the chief complaint have been reported. Of these five cases, 1 early cancer patient (8) and 3 advanced cancer patients exhibited liver abscesses alone (9,10,13) and 1 advanced cancer patient exhibited multiple systemic abscesses (12). Fever was the main symptom in all cases, with weight loss, malaise and nausea/vomiting also observed (8)(9)(10)12,13). In addit...

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Early rectal cancer accompanied by multiple systemic abscesses: A case report

et al. 2015

View full text Add to dashboard Cite

show abstract

Pyogenic Liver Abscesses Secondary to Carcinoma of the Sigmoid Colon

Yokota¹,

Iwamoto²,

Watanabe³

et al. 2005

Upsala Journal of Medical Sciences

View full text Add to dashboard Cite

We report a case of liver abscesses associated with sigmoid colon cancer in an 81-yearold woman. The patient was referred to our hospital because of a tumorous lesion of the sigmoid colon. Five days before the scheduled operation, she presented abdominal pain, fever and chill. Imaging scans revealed multiple liver abscesses in both lobes, which were successfully treated with intravenously administered antibiotics. Two weeks later, the patient underwent laparoscopic-assisted sigmoidectomy. Nineteen cases of liver abscess associated with colonic cancer have been reported during the past ten years in Japan, and we report the clinical features of these cases in this paper. An aggressive search for the underlying cause of pyogenic liver abscess should be an integral part of the definitive treatment of this disease.

show abstract