A case of angiomyolipoma of the lower lip

Nakabayashi, Motoki; Kodani, Isamu; Takubo, Kazuko; Kimura, Kazunori; Sakai, Hiroatsu; Ryoke, Kazuo

doi:10.1016/j.ajoms.2013.02.003

Cited by 4 publications

(11 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our results agree with positivity described for SMA and negativity for HMB-45 in other cases of oral AML [1,3,4]. Immunoreactivity for CD-34 is similar to the results of Nakabayashi et al [8], and focal positivity for S-100 was also reported in a case of oral angiomyolipoma by Alvarez et al [1].…”

Section: Discussionsupporting

confidence: 92%

“…The smooth muscle cells of renal and liver AML differ from normal smooth muscle cells in that they react with the HMB-45 antibody. Because no HMB-45 positive immunoreactivity is found in head and neck tumors, this antibody is useful in diagnosis of AML of these sites [8]. The present case was positive for CD-34 and SMA, focally positive for S-100 and was negative for HMB-45.…”

Section: Discussionmentioning

confidence: 49%

“…Angiomyolipoma is extremely rare in the oral cavity. To our knowledge, only 18 cases of angiomyolipoma have been reported in oral cavity till now; 6 cases in lower and upper lips, 6 cases in tongue, 5 cases on the palate and 1 in cheek [4,7,8]. A well circumscribed mass with no invasion is the most common clinical appearance.…”

Section: Discussionmentioning

confidence: 98%

“…A well circumscribed mass with no invasion is the most common clinical appearance. However, the difference in the percentage of tissue components, make a difference in elasticity or color of the lesion [8]. Besides the present of three main components of the tumor in microscopic features, IHC staining has a very important role in diagnosis of oral AML.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Angiomyolipoma of the Oral Cavity: A Rare Case Report

Amanpour¹,

Zarei²,

Faryabi³

et al. 2019

JDMS

View full text Add to dashboard Cite

Angiomyolipoma (AML) is a rare, benign tumor composed of thick-wall blood vessels, smooth muscle component and mature adispose tissue. Differentiation from other benign and malignant mesenchymal lesions of oral cavity depends on recognition of these three histologic components, and immunohistochemical (IHC) techniques are also helpful. This tumor arise from perivascular epithelioid cells (PEComas) and kidneys followed by liver are the main locations of this soft tissue tumor. AMLs are rarely found in oral cavity and few case reports of oral AML have been reported in the literature. We report the first case of concurrent occurrence of AML of the tongue and peripheral giant cell granuloma of the gingiva in a 59-year-old patient. Clinically it was presented as a painless nodular mass with a smooth surface on the dorsal of the tongue. Based on histopathologic features and IHC staining the diagnosis of oral AML was done. The other lesion was a small sessile mass in interdental papillae of the lower incisors and microscopic examination showed the histologic features of a peripheral giant cell granuloma. Concurrent occurrence of PGCG which is a reactive mucosal hyperplasia and AML in our patient, could show the probable role of local trauma in the pathogenesis of these lesions.

show abstract

Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 49%

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Angiomyolipoma of the Oral Cavity: A Rare Case Report

Amanpour¹,

Zarei²,

Faryabi³

et al. 2019

JDMS

View full text Add to dashboard Cite

show abstract

“…Another case of AML in the tongue was diagnosed as a lipoma by needle biopsy (Table 1). Although immunostaining of HMB-45 with specimens obtained by needle biopsy can be helpful in the diagnosis of renal AML [15,16], AMLs in the head and neck region are generally negative for HMB-45 [17]. In the presented case, contrast-enhanced CT showed that the tumor had rich blood flow.…”

Section: Discussionmentioning

confidence: 94%