A case of ARF after chromopertubation with povidone iodine

Gautam, Savita S.; Gautam, Rajesh

doi:10.18203/2320-1770.ijrcog20182923

Cited by 5 publications

(4 citation statements)

References 8 publications

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“…Toxicity of another solution, cetyl pyridinium chloride, is noticed with vomiting, diarrhea, and abdominal pain. Ingestion of this solution in concentrated form may produce burns of the mouth, pharynx, and esophagus [51]. Additionally, hemorrhagic GI tract necrosis and peritonitis have also been reported [51].…”

Section: Discussionmentioning

confidence: 99%

“…Ingestion of this solution in concentrated form may produce burns of the mouth, pharynx, and esophagus [51]. Additionally, hemorrhagic GI tract necrosis and peritonitis have also been reported [51]. Prolonged exposure of common constituents of oral rinses like essential oils, menthol, thymol can act as potential allergens in various ethnical races [52].…”

Section: Discussionmentioning

confidence: 99%

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Oral rinses in growth inhibition and treatment of Helicobacter pylori infection

et al. 2020

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Background: Helicobacter pylori (H. pylori) is well-known for its role in chronic gastritis and gastric cancer. Eradication of these carcinogenic bacteria from the gut is one of the challenges for clinicians. The complexity of treatment mainly owes to antibiotic resistance and relapse due to an additional reservoir in the oral cavity. Our study emphases the isolation of H. pylori from distinct habitats of the gut microenvironment (gastric biopsy and gastric juice) and its subsequent characterization. We have also evaluated the effect of various oral rinses on isolated H. pylori from different anatomical locations of included subjects. Results: The possible strains isolated from two different habitats of the same subject shows a striking difference in their growth pattern. Promisingly, some of the included oral rinses are efficient in growth inhibition as per recommended 30 s treatment. The subsequent evaluation shows that oral rinse B (among A-E) is most effective and down-regulates the expression of one of the potent H. pylori gene, CagA, in the infected gastric adenocarcinoma (AGS) cells. Conclusion:Our study, for the first time, revealed that H. pylori, isolated from the different habitat of the same subject, show a different growth pattern. The expression of H. pylori pathogenic gene (CagA) was down-regulated by the use of oral rinses. Hence, oral rinses will reduce the H. pylori in the oral cavity and help to control its migration from oral to the gastric compartment and may be used as an adjuvant treatment option for its reinfection.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Oral rinses in growth inhibition and treatment of Helicobacter pylori infection

et al. 2020

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“…However, such studies were conducted in the 1980s; hence, further investigations with modern detection techniques are needed in long term follow-up. Research on povidone-iodine, reveals that it can cause acute renal failure, mainly when absorbed through mucosal surfaces [50,51]. Even diluted solutions of povidone-iodine (0.1 to 20%) are toxic to human fibroblasts, granulocytes, and monocytes [52].…”

Section: Discussionmentioning

confidence: 99%

Oral rinses in growth inhibition and treatment of Helicobacter pylori infection

Kashyap

Baral

Verma

et al. 2020

Preprint

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Background Helicobacter pylori ( H. pylori ) is well-known for its role in chronic gastritis and gastric cancer. Eradication of these carcinogenic bacteria from the gut is one of the challenges for clinicians. The complexity of treatment mainly owes to antibiotic resistance and relapse due to an additional reservoir in the oral cavity. Our study emphases the isolation of H. pylori from distinct habitats of the gut microenvironment (gastric biopsy and gastric juice) and its subsequent characterization. We have also evaluated the effect of various oral rinses on isolated H. pylori from different anatomical locations of included subjects.Results The possible strains isolated from two different habitats of the same subject shows a striking difference in their growth pattern. Promisingly, some of the included oral rinses are efficient in growth inhibition as per recommended 30 sec treatment. The subsequent evaluation shows that oral rinse B (among A-E) is most effective and down-regulates the expression of one of the potent H. pylori gene, CagA, in the infected gastric adenocarcinoma (AGS) cells.Conclusion Our study, for the first time, revealed that H. pylori, isolated from the different habitat of the same subject, show a different growth pattern. The expression of H. pylori pathogenic gene (CagA) was down-regulated by the use of oral rinses. Hence, oral rinses will reduce the H. pylori in the oral cavity and help to control its migration from oral to the gastric compartment and may be used as an adjuvant treatment option for its re-infection.

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“…However, such studies were conducted in the '80s, hence, further investigations with modern detection techniques are needed in long term follow-up. Investigation on povidone-iodine, reveals that it can cause acute renal failure, especially when absorbed through mucosal surfaces [44,45]. Even dilute solutions of povidone-iodine (0.1 to 20%) are toxic to human fibroblasts, granulocytes, and monocytes [46].…”

Section: Discussionmentioning

confidence: 99%

Differential effect of chemical compounds on Helicobacter pylori growth and subsequent apoptosis

Kashyap¹,

Baral²,

Verma³

et al. 2019

Preprint

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Background Helicobacter pylori (H. pylori) is well-known for its role in chronic gastritis and gastric cancer. Eradication of these carcinogenic bacteria from the gut is one of the major challenges for the clinicians. The complexity of treatment is mainly owing to, antibiotic resistance and relapse due to extra gastric reservoir in the oral cavity. Our study focuses on the isolation of H. pylori from distinct habitats (gastric biopsy and gastric juice) of the gut microenvironment and its subsequent characterization. Further, we have also evaluated the effect of various plaque control agents on isolated strains of H. pylori.Results The strains isolated from two different habitats of the same subject shows a striking difference in their growth pattern. Promisingly, some included chemicals are effective in growth inhibition after recommended 30 sec treatment. The subsequent evaluation shows that chemical B (out of chemical A, B, C, D and E) is the most effective and downregulate the expression of CagA in the infected AGS cells.Conclusion For the fast time, in our study the pylori isolated from different habitat of the same subject shows differential growth pattern. Nowadays, antibiotic resistance and relapse of H. pylori make it difficult to eradicate the bacteria from gastric as well as oral reservoir. Thus, this study may help to reduce the bacteria in their oral reservoir and also control the H. pylori migration from oral to gastric compartment.

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A case of ARF after chromopertubation with povidone iodine

Cited by 5 publications

References 8 publications

Oral rinses in growth inhibition and treatment of Helicobacter pylori infection

Oral rinses in growth inhibition and treatment of Helicobacter pylori infection

Oral rinses in growth inhibition and treatment of Helicobacter pylori infection

Differential effect of chemical compounds on Helicobacter pylori growth and subsequent apoptosis

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