Povidone iodine is a widely-used antiseptic agent, especially for cutaneous lesions. Despite its apparent innocuousness, some cases of acute renal failure are reportedly due to iodine toxicity. Authors report a case of an acute renal failure secondary to povidone iodine exposure in a 22-year-old woman. She underwent a hysteroscopy for diagnosis of secondary sterility with bilateral tubal block in hysterosalpingogram, and povidone iodine was used as the contrast agent. She developed acute renal failure with oliguria, later on anuria during the postoperative period. Treatment with diuretics and hemodialysis led to a favourable outcome and return of normal kidney function. Mucosal administration of povidone iodine appears to lead to greater iodine toxicity than cutaneous administration. The clinical feature of this patient suggested tubular necrosis caused by iodine, after the other possible causes of acute renal failure were ruled out. Acute renal failure secondary to povidone iodine administration is possible, especially through mucosal surfaces. Outcome is favourable after the conclusion of exposure and symptomatic treatment.

Background: In many areas of world, hypertensive disease in pregnancy is the single most common cause of maternal death. Pregnancy associated hypertension remains unsolved despite decades of intensive research and remains the most significant problem in obstetrics. The aim of present study is to evaluate the variations and potential clinical use of second trimester serum markers for the detection of pre-eclampsia.Methods: In an observational study, estimations of serum of human chorionic gonadotropin (β-hCG) were done in 347 randomly selected women at 13-20 weeks of gestation in august 2015 to may 2016. Multiple of median (MOM) was calculated from charts of norms available for that weeks of pregnancy. The subjects were followed up till delivery for the development of hypertension in pregnancy and results analysed statistically with Chi-square test.Results: Out of 347, 47 women developed hypertyension and 2MOM of β hCG was significantly (P<0.001) elevated in those who developed hypertension compared to normotensive women. In our study group a significant associations between elevations in second trimester β-hCG and development of hypertension was observed. Thus with second trimester serum marker study, prediction of pre- eclampsia is possible at incipient stage and adverse pregnancy outcome can be minimized.Conclusions: Maternal serum β-hCG level was found to be significantly higher in hypertensive group than normal group.

Caesarean scar ectopic is one of the rarest of all ectopic pregnancies. The incidence of caesarean scar pregnancy (CSP), which was extremely rare till recent times, has been rising steadily. Case have more of such cases being published in medical literature now. It is defined as when a blastocyst implants on a previous caesarean scar. The incidence of caesarean scar ectopic has increased due to increase in number of caesarean deliveries. Early diagnosis of this can be done by using ultrasound. It is very important because a delay can lead to increased maternal morbidity and mortality. Early diagnosis leads to prompt management and improves the outcome by allowing preservation of future fertility. Magnetic resonance imaging (MRI) has important role when sonography is equivocal or inconclusive before therapy or intervention. Case are reporting a rare case of G2P1l1 with previous one caesarean delivery, diagnosed as caesarean scar ectopic pregnancy with the help of sonography. Patient underwent laparotomy and on histopathological examination caesarean scar pregnancy was confirmed. Due to the rarity of this condition, there are no specific guidelines available for its management.