A case of ‘blue skin’ and ‘dark urine’

Arora, Sandeep; Sodhi, Neha; Harith, Arun Kumar; Kapoor, Umesh

doi:10.1016/j.mjafi.2017.06.009

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…Long-term deposition of HGA in bone tissue can cause spinal and joint diseases, and severe destruction of cartilage in late stage and can result in crippling osteoarthropathy[ 6 , 7 ]. Part of the excess HGA is excreted by urine and oxidized into melanin in the air, making the urine black[ 8 ]. Urine HGA is currently considered as the gold standard for the diagnosis of the disease[ 9 ].…”

Section: Discussionmentioning

confidence: 99%

Ochronotic arthropathy of bilateral hip joints: A case report

Min¹,

Rafi²,

Wang³

et al. 2023

World J Clin Cases

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BACKGROUND Ochronosis, also known as alkaptonuria, is a rare autosomal recessive self-metabolic disease arising from deficiency of homogentisate 1,2 dioxygenase enzyme. It affects several organs and muscoskeletal structures. We herein report a case of a patient who presented with severe hip arthropathy complicated with late stage ochronosis. CASE SUMMARY A 56-year-old male patient was admitted in our department in 2019 with complaints of chronic low backache and left hip pain. After the required investigations were done, lumbar disc herniation and severe hip arthritis were the initial diagnosis. A total left hip arthroplasty was performed. Ochronotic osteoarthritis was only obtained post-surgery as confirmatory diagnosis. He was again admitted mid 2022 with the same complaints on the right hip. Subsequently, he underwent a total right hip arthroplasty. Post-operative recovery and follow-ups were deemed very satisfactory. CONCLUSION Ochronosis is an unusual diagnosis for a patient who presents with typical hip arthritis. Thus, unless meticulous history taking and advanced laboratory tests, the diagnosis can easily be missed by surgeons.

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Section: Discussionmentioning

confidence: 99%

Ochronotic arthropathy of bilateral hip joints: A case report

Min¹,

Rafi²,

Wang³

et al. 2023

World J Clin Cases

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“…Alteration of urine color can be due to a variety of causes such as poisonous materials, food coloration substances, medications, UTIs, urinary stones, hematuria (blood in the urine), hemoglobinuria (hemoglobin in the urine), and porphyria [ [16] , [17] , [18] , [19] , [20] ]. None of the medications that our patient takes are reported to cause urine discoloration.…”

Section: Discussionmentioning

confidence: 99%

Violet discoloration of urine: A case report and a literature review

Saraireh

Gharaibeh

Araydah

et al. 2021

Annals of Medicine &Amp; Surgery

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Background Purple Urine Bag Syndrome (PUBS) is an uncommon event that can be described as purple discoloration of urine due to a series of chemical reactions induced by Urinary Tract Infections (UTIs). PUBS has been reported in the past but still remains unrecognized by healthcare givers leading to misdiagnosis and inappropriate management. We report our case alongside a literature review of previously published cases. Case presentation We present the first case report of Purple Urine Bag Syndrome in Jordan of a catheterized 80-year-old wheel-chaired female with a history of type 2 Diabetes Mellitus (DM), stage 5 Chronic Kidney Disease (CDK), Hypertension, and ischemic stroke. Her condition was initially misdiagnosed for hematuria but later on was correctly diagnosed with PUBS. She was treated with a course of appropriate antibiotic and by changing her urinary catheter and bag. The patient returned for a follow up visit and her problem resolved with the color of her urine in the urine bag returning back to normal. Clinical discussion PUBS is an uncommon event that occurs in association with UTIs. Such cases are mostly seen in elderly catheterized patients with other risk factors. Conclusion Purple Urine Bag Syndrome can be managed by changing urinary catheter, and by the administration of appropriate antibiotics. Such event can be easily misdiagnosed thus leading to unnecessary and consuming measures. Creating a better awareness of this condition among physicians and healthcare givers is essential for better patient outcomes.

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