A case of cerebral salt-wasting syndrome associated with aseptic meningitis in an 8-year-old boy

Inatomi, Jun; Yokoyama, Yoshiki; Sekine, Takashi; Igarashi, Takashi

doi:10.1007/s00467-007-0679-8

Cited by 5 publications

(7 citation statements)

References 12 publications

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“…Schwartz et al [2] have reported a syndrome of inappropriate anti-diuretic hormone secretion (SIADH) in central nervous system disorders. Interestingly, CSWS syndrome is reported more frequently in patients with acute central nervous system disorder as in recent reports [3].…”

Section: Introduction mentioning

confidence: 59%

Cerebral salt wasting syndrome in a child with SSPE

et al. 2015

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Cerebral salt-wasting syndrome is a disorder characterized by severe hyponatremia, volume depletion, and elevated brain natriuretic peptide but normal antidiuretic hormone levels. In this manuscript, we report the case of a six-year-old patient with cerebral salt-wasting syndrome associated with subacute sclerosing panencephalitis. The patient showed dehydration, tachycardia, pyrexia, polyuria, severe hyponatremia, and a significant loss of urinary sodium. He was successfully treated with sodium and fluid replacement therapy.

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Section: Introduction mentioning

confidence: 59%

Cerebral salt wasting syndrome in a child with SSPE

et al. 2015

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“…It mimics the findings in the syndrome of inappropriate anti-diuresis, except that salt-wasting is the primary defect with the ensuing volume depletion leading to a secondary release of vasopressin [8,14]. It has been suggested that renal salt wasting of central origin results from increased secretion of a natriuretic peptide with subsequent suppression of aldosterone synthesis.…”

Section: Hyponatremiamentioning

confidence: 76%

“…It has been suggested that renal salt wasting of central origin results from increased secretion of a natriuretic peptide with subsequent suppression of aldosterone synthesis. The clinical distinction between cerebral salt wasting and inappropriate activity of vasopressin is not always simple to make since the true volume status is sometimes difficult to ascertain [8,14]. …”

Section: Hyponatremiamentioning

confidence: 99%

Body fluids and salt metabolism - Part II

et al. 2010

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There is a high frequency of diarrhea and vomiting in childhood. As a consequence the focus of the present review is to recognize the different body fluid compartments, to clinically assess the degree of dehydration, to know how the equilibrium between extracellular fluid and intracellular fluid is maintained, to calculate the effective blood osmolality and discuss both parenteral fluid maintenance and replacement.

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“…However, there are a few case reports in literature that describe the association of CSW with infection. [9] The mechanism by which cerebral disease leads to renal salt wasting is not well known. Decisions regarding treatment can be taken by investigating the levels of natriuretic peptides (ADH, ANP, BNP, renin-aldosterone axis elements).…”

mentioning

confidence: 99%

“…Doses of 0.1–0.4 mg/day fludrocortisone with saline and water replacement increased Na concentrations to normal serum levels. [49] We could not obtain fludrocortisone and other steroids which have higher mineralocorticiod activity than prednisolone, therefore, 2 mg/kg/day prednisolone doses were used. Sodium levels increased to 136 mmol/L with this additional therapy.…”

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confidence: 99%