A Case of Clear Cell Sarcoma of the Kidney

Franco, Arie; Dao, Tuan Vu; Lewis, Kristopher Neal; Biddinger, Paul

doi:10.3941/jrcr.v5i2.630

Cited by 8 publications

(10 citation statements)

References 9 publications

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“…A predominantly solid heterogeneous renal mass with cystic-appearing areas representing cysts and mucoid material is seen (Fig 14) (8,40,42,(76)(77)(78). At US, the cysts are anechoic (Fig 15) (76,78,79). Occasionally, large fluid-filled spaces with echogenic septa similar to multilocular cystic renal tumor may predominate (79).…”

Section: Imaging Featuresmentioning

confidence: 99%

“…Distant metastases are found at presentation in 5%-18% of patients (74,76,81,82). The most common sites at presentation are lymph nodes (30%) and bone (13%-20%), with the lung, brain, and liver less frequent (Fig 14) (73,75,82).…”

Section: Imaging Featuresmentioning

confidence: 99%

“…The most common sites at presentation are lymph nodes (30%) and bone (13%-20%), with the lung, brain, and liver less frequent (Fig 14) (73,75,82). Due to its propensity for osseous metastases, bone scintigraphy should be performed once the diagnosis is established (76,83). Bone metastases may be lytic, sclerotic, or mixed at radiography (42).…”

Section: Imaging Featuresmentioning

confidence: 99%

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Renal Tumors of Childhood: Radiologic-Pathologic Correlation Part 1. The 1st Decade:From the Radiologic Pathology Archives

Chung¹,

Graeber²,

Conran³

2016

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Wilms tumor is the second most common pediatric solid tumor and by far the most common renal tumor of infants and young children. As most tumors are large at presentation and are treated with nephrectomy, the role of imaging is primarily in preoperative planning and evaluation for metastatic disease. However, with treatment protocols increasingly involving use of preoperative (neoadjuvant) chemotherapy (the standard in Europe) and consideration of nephron-sparing surgery, the role of imaging is evolving to include providing initial disease staging information and a presumptive diagnosis to guide therapy. Differential diagnostic considerations include lesions that are clinically benign and others that require more intensive therapy than is used to treat Wilms tumor. In part 1 of this article, the unique histologic spectrum of renal neoplasms of infants and young children is reviewed with emphasis on radiologic-pathologic correlation. Part 2 will focus on renal tumors of older children and adolescents.

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Section: Imaging Featuresmentioning

confidence: 99%

Section: Imaging Featuresmentioning

confidence: 99%

Section: Imaging Featuresmentioning

confidence: 99%

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Renal Tumors of Childhood: Radiologic-Pathologic Correlation Part 1. The 1st Decade:From the Radiologic Pathology Archives

Chung¹,

Graeber²,

Conran³

2016

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“…(MGG 3 40) [Color figure can be viewed at wileyonlinelibrary.com] DAS ET AL. | 763abdominal masses and to assess the resectability of these tumors.However, these imaging studies are sometimes nonspecific 9. About 5%-10% of tumors radiologically diagnosed as Wilms' tumor may prove to be benign.…”

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confidence: 99%

FNAC aided diagnosis of clear cell sarcoma of kidney: Report of two cases in infants

Das

Dalal³

et al. 2017

Diagnostic Cytopathology

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Clear cell sarcoma of kidney (CCSK) is a rare aggressive malignant renal neoplasm with a high metastatic potential. Its outcome has however, improved with the advent of doxorubicin based neoadjuvant chemotherapy. Here, we present two cases of CCSK in infants diagnosed on cytology followed by nephrectomy. The first case presented in the neonatal period and had the unusual histological finding of islands of cartilage. The second case presented at the age of eight months. The possibility of CCSK should, therefore, be considered in the differential diagnoses of renal masses in infants as well as neonates. Diagn. Cytopathol. 2017;45:761-765. © 2017 Wiley Periodicals, Inc.

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“…5 Nevertheless, there are no tumor specific markers for clear cell sarcoma of kidney, which makes the diagnosis difficult. 6 However, Argani et al 7 reported that vimentin is readily demonstrable in nearly all specimens and BCl 2 is demonstrable in some but other markers EMA, CK, S-100, desmin, CD34 and CD99 are consistently negative. Our case showed vimentin and BCl 2 positive and EMA negative.…”

Section: Discussionmentioning

confidence: 98%