A case of ethanol‐induced systemic allergic dermatitis

Chu, Grace; Murad, Ari

doi:10.1111/cod.12668

Cited by 12 publications

(4 citation statements)

References 19 publications

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“…Cutaneous reactions induced by ethanol include contact dermatitis and urticaria. 2 , 3 Contact urticaria seems very rare and to the best of our knowledge, two cases were reported after application of alcohol‐based perfumes and hand sanitizers. 4 , 5 The mechanisms are partially understood and could be immunological contact urticaria that reflects type I hypersensitivity reactions or non‐immunological contact urticaria that is caused by vasogenic mediators.…”

Section: Discussionmentioning

confidence: 96%

“…Alcohol is widely used in beverages, antiseptics, detergents, pharmaceuticals and cosmetics. Cutaneous reactions induced by ethanol include contact dermatitis and urticaria 2,3 . Contact urticaria seems very rare and to the best of our knowledge, two cases were reported after application of alcohol‐based perfumes and hand sanitizers 4,5 .…”

Section: Discussionmentioning

confidence: 99%

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Contact urticaria to ethanol contained in a hand sanitizer

et al. 2022

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Contact urticaria to ethanol contained in a hand sanitizer

et al. 2022

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“…Permeation studies of IDV across human cadaver skin showed significantly enhanced transdermal flux from ethanolic liposomes than from an ethanolic drug solution, conventional liposomes, or a plain drug solution [77]. However, the local effects of ethanol on skin could be a challenge for chronic use in some patients [78].…”

Section: Nanocarriers Used In Hiv Chemotherapymentioning

confidence: 99%

Recent developments of nanotherapeutics for targeted and long-acting, combination HIV chemotherapy

Gao

Kraft

et al. 2019

European Journal of Pharmaceutics and Biopharmaceutics

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Combination antiretroviral therapy (cART) given orally has transformed HIV from a terminal illness to a manageable chronic disease. Yet despite the recent development of newer and more potent drugs for cART and suppression of virus in blood to undetectable levels, residual virus remains in tissues. Upon stopping cART, virus rebounds and progresses to AIDS. Current oral cART regimens have several drawbacks including (1) challenges in patient adherence due to pill fatigue or side-effects, (2) the requirement of life-long daily drug intake, and (3) limited penetration and retention in cells within lymph nodes. Appropriately designed injectable nano-drug combinations that are long-acting and retained in HIV susceptible cells within lymph nodes may address these challenges. While a number of nanomaterials have been investigated for delivery of HIV drugs and drug combinations, key challenges involve developing and scaling delivery systems that provide a drug combination targeted to HIV host cells and tissues where residual virus persists. With validation of the drug-insufficiency hypothesis in lymph nodes, progress has been made in the development of drug combination nanoparticles that are long-acting and targeted to lymph nodes and cells. Unique drug combination nanoparticles (DcNPs) composed of three HIV drugs-lopinavir, ritonavir, and tenofovir-have been shown to provide enhanced drug levels in lymph nodes; and elevated drug-combination levels in HIV-host cells in the blood and plasma for two weeks. This review summarizes the progress in the development of nanoparticle-based drug delivery systems for HIV therapy. It discusses how injectable nanocarriers may be designed to enable delivery of drug combinations that are long-lasting and target-selective in physiological contexts (in vivo) to provide safe and effective use. Consistent drug combination exposure in the sites of residual HIV in tissues and cells may overcome drug insufficiency observed in patients on oral cART.

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“…One of the examples of hydrocarbon causing toxic affect to the environment is the accidental crude oil spill in seawater [4]. It was reported that a black bag containing 15 to 20 liters of oil was dumped in the seawater of Redang island in Terengganu [5]. The marine life along the shore was affected, especially turtles landing on the island to lay eggs.…”

Section: Introductionmentioning

confidence: 99%

Isolation and Identification of Carbazole Degrading Bacteria from Lake Water

Khan¹

2021

Promising Techniques for Wastewater Treatment and Water Quality Assessment

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Heterocyclic hydrocarbon compounds have been identified as one of the major components of water pollution that occurs as a result of urbanization. It has been known that the presence of these compounds is hazardous and remain in the environment for a long period of time. This study was conducted to isolate and identify heterocyclic hydrocarbon degrading bacteria from lake water by genomic DNA extraction and sequencing as well as measure the degradation rate of the bacteria using Gas Chromatography Flame-Ionization Detector (GC-FID). The water sample was collected from west campus lake of Universiti Malaysia Sarawak where six strains of bacteria that has degrading ability was isolated using sub-culturing technique on MSM double layer agar plates. The genomic DNA of bacteria designated as strain IM1, IM2, IM3, IM4, IM5 and IM6 were extracted and amplified using Polymerase Chain Reaction (PCR). The isolates were then sequenced and were identified as Bradyrhizobium sp., Ochrobactrum sp., Pseudomonas aeruginosa sp. and Burkholderia sp. All six isolates possessed the ability to utilize carbazole as sole carbon and energy source as the degradation rate of carbazole was measured using GC-FID analysis. After 12 days of incubation, IM2 showed 96.37% degradation while the other five isolates were able to degrade 100% of the carbazole. Thus, bacteria isolated from this study may provide great benefit for bioremediation.

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A case of ethanol‐induced systemic allergic dermatitis

Cited by 12 publications

References 19 publications

Contact urticaria to ethanol contained in a hand sanitizer

Contact urticaria to ethanol contained in a hand sanitizer

Recent developments of nanotherapeutics for targeted and long-acting, combination HIV chemotherapy

Isolation and Identification of Carbazole Degrading Bacteria from Lake Water

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