A Case of Giant Sebaceous Gland Carcinoma Without Adequate Treatment

Enomoto, Eriko; Kamura, Yumi; Nohara, Masako; Kaneko, Akira; Tsuji, Hideki; Hasegawa, Hiromasa; Sugitani, Masahiko

doi:10.1016/s0021-5155(00)00375-0

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“…Ophthalmologists recommend that in the case of patients with atypical symptoms, recurrence, older age, and lesions that are increasing in size, the excised chalazion be sent for histopathological examination to exclude malignancy. [1][2][3][4][5] FNAC is a rapid, safe, and reliable means of documenting a tissue diagnosis of chalazion and excluding malignancy, allowing treatment to be initiated with confidence. The…”

Section: Discussionmentioning

confidence: 99%

“…It is well known that malignant eyelid lesions and chalazia may often present with similar clinical parameters so that clinical misdiagnosis sometimes represents a relevant and dreaded pitfall. [1][2][3][4][5] The cytomorphology of chalazion has not been described. Fine-needle aspiration cytology (FNAC) has been applied as a diagnostic technique to neoplastic lesions of the eyelid and is safe and reliable.…”

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confidence: 99%

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Cytopathology of chalazia

Dhaliwal

Arora

Singh

et al. 2004

Diagnostic Cytopathology

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Chalazion is a common inflammatory condition of the eyelid, usually treated on the basis of clinical diagnosis alone. Preoperative exclusion of malignancy in chalazia with atypical clinical presentation could prevent unwarranted surgery. This is a retrospective study of aspirates from 16 patients with chalazia having an atypical clinical presentation. Smears were stained with May-Grünwald Giemsa. Two broad patterns of granulomatous inflammation reflecting the spectrum of changes in the course of the disease were seen. Nine smears had mixed-cell granulomas consisting of neutrophils, lymphocytes, plasma cells, macrophages, giant cells, and granulation tissue. Seven smears had suppurating granulomas characterized by epithelioid cell granulomas with numerous neutrophils in a proteinaceous background. Fine-needle aspiration cytology of chalazia with atypical clinical presentation provides a rapid, safe, and reliable means of documenting the diagnosis and excluding malignancy.

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confidence: 99%

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confidence: 99%