A Case of Invasion of Muscularis Propria of Gastric Inflammatory Fibroid Polyp

Lee, Ji Hyeon; Yoo, Jin Sae; Jung, Hae-Yun; Kim, Hee Man; Ryu, Hun; Cho, Mee Yon; Kim, Hyun Soo

doi:10.7704/kjhugr.2015.15.4.254

Cited by 7 publications

(4 citation statements)

References 10 publications

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“…The lesion was centered in the submucosa and destroyed the muscularis propria. There have also been three cases of invasive IFPs (Harima et al, 2018; Lee et al, 2015; Tajima & Koda, 2018) and two cases of local recurrence (Spencer, 1969; Zinkiewicz et al, 2014) reported. Because some PDGFRA-expressing cells have been discovered at the same sites in the guts of mice (even into maturity), Tajima and Koda (2018) have demonstrated that the cellular origin of IFP is “villous clusters,” which are clusters of PDGFRA-expressing mesenchymal cells spreading along the basement membrane of intestinal villi in mouse embryos.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case Report of Recurrent Inflammatory Fibroid Polyp in the Ileum

Xv¹,

Tao²,

Vitito³

2022

Gastroenterology Nursing

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Inflammatory fibroid polyp (IFP) is a rare clinically benign mesenchymal tumor originating in the submucosa of the gastrointestinal tract. It has been generally considered to bear no malignant or metastatic potential and can be cured after resection. Herein, we present an unusual case of an IFP in the ileum showing extension to the muscularis propria and recurring in 3 years after endoscopic submucosal dissection (ESD) and surgical resection. A 41-year-old woman was admitted to the emergency department due to abdominal pain, abdominal distention, and vomit for 4 days. She had an ESD 3 years ago as a result of IFPs in the middle esophagus and gastric horn. She also had a small bowel resection for intussusception resulting from IFP 2 years previously. She had no family history of IFP. An intussusception was found 1 m away from the ileocecal valve and a red tumor about 5 cm in diameter was revealed after manipulation reduction, with several small polypoid protuberant masses in the adjacent intestine. The diseased bowel was excised and a primary side-to-side anastomosis was performed. The morphological and immunoprofile features were typical of IFP. The patient was required to fast after operation until she farted, and she was discharged 1 week later, asymptomatic. Therefore, IFP might show its aggressively neoplastic potential with infiltrative growth patterns and recur locally after inadequate resection. A sufficient surgical resection is recommended when the lesion has been found definitely to invade the muscularis and even the subserosa. However, more studies are required to seek for the exact etiology and mechanism of its invasiveness and recurrence due to the scarcity of current reports.

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Section: Discussionmentioning

confidence: 99%

A Rare Case Report of Recurrent Inflammatory Fibroid Polyp in the Ileum

Xv¹,

Tao²,

Vitito³

2022

Gastroenterology Nursing

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“…Although IFPs are biologically regarded benign and noninvasive lesions [22], few cases have been observed to invade the muscularis propria layer [23]. With regard to gastric IFPs, only three invasive cases have been reported in the literature described in 2015 [24,25]. Here, we describe a case of an invasive IFP involving the small bowel.…”

Section: Discussionmentioning

confidence: 88%

Inflammatory Fibroid Polyp in a 48-Year-Old Male: A Rare Cause of Intussusception

Karuhanga

Ngimba²,

Yahaya

2020

Case Reports in Surgery

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Inflammatory fibroid polyp is a neoplastic condition affecting the gastrointestinal tract and particularly the gastric antrum. It is virtually a benign submucosal mass comprising mesenchymal cells and numerous small blood vessels with inflammatory cells and commonly eosinophils. Patients with inflammatory fibroid polyps usually present clinically with mechanical intestinal obstruction with or without intussusception. Herein, we present a case of a 48-year-old male with a known history of schizophrenia who presented with mechanical intestinal obstruction following intussusception due to inflammatory fibroid polyp involving the proximal jejunojejunal part of the jejunum.

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“…Therefore, further diagnostics and follow up are not recommended. However, recently three case reports have been published that showed the invasion of IFP through the muscularis propria layer, one in the ileum [79] and two in the stomach [66,80].…”

Section: Discussionmentioning

confidence: 99%

Inflammatory Fibroid Polyp of the Small Intestine: A Case Report and Systematic Literature Review

Ivaniš¹,

Tomas

Vranić

et al. 2020

JGLD

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Aim: Starting from a case presentation, this review aims to present literature data on inflammatory fibroid polyps (IFPs) of the small intestine. Methods: Case report and systematic review. A comprehensive systematic review of English literature using PubMed was conducted, based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The used key words were: “inflammatory fibroid polyp” or “Vanek”, including only cases with IFPs localized of the small intestine, published from 1976 to 2019. Results: We present a case of a 38-year old patient with intestinal IFP presenting with acute abdomen due to intussusception diagnosed with ultrasound (US) based on a target sign and visible solid tumor in the small intestine leading to prompt surgical treatment. A diagnosis of IFP was made based on the pathohistological findings. Moreover, a systematic review of small intestine IFPs was conducted which is, to our knowledge, the first comprehensive systematic literature review on this topic. The analysis included 53 case reports or case series concerning 77 cases of small bowel IFPs. The patients were aged from 4 to 75 years (average 45.2), with a female predominance (59.7%). The most common localization was the ileum in 77.9% cases, followed by the jejunum (13%) and the duodenum (6.5%). The most common clinical presentation was abdominal pain due to intussusception (63.6%). Regarding diagnostic methods, computed tomography (CT) was frequently used as primary diagnostic method (26%) followed by exploratory laparotomy (16.9%), endoscopy (7.8%) and US (6.5%). Combination of US and CT contributed to the diagnosis in 9.1% of cases. The majority of cases were treated surgically (92.21%), while only a minority benefited of minimally invasive techniques such as endoscopy. Conclusions: Small bowel IFPs, ones of the least common benign tumors, are characterized by variable clinical signs and symptoms and can potentially lead to serious consequences for the patient.

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A Case of Invasion of Muscularis Propria of Gastric Inflammatory Fibroid Polyp

Cited by 7 publications

References 10 publications

A Rare Case Report of Recurrent Inflammatory Fibroid Polyp in the Ileum

A Rare Case Report of Recurrent Inflammatory Fibroid Polyp in the Ileum

Inflammatory Fibroid Polyp in a 48-Year-Old Male: A Rare Cause of Intussusception

Inflammatory Fibroid Polyp of the Small Intestine: A Case Report and Systematic Literature Review

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