A Case of Jejunal Intussusception caused by Burkitt Lymphoma in an Acquired Immunodeficiency Syndrome Patient

Baek, Dae Youb; Heo, Dae-Hyuk; Oh, Seung-Yong; Hwang, Joo Hee; Hwang, Jeong Hwan; Park, Ho Sung; Lee, Chang Seop

doi:10.3947/ic.2018.50.1.51

Cited by 4 publications

(3 citation statements)

References 16 publications

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“…We identified 12 prior reports of adult intussusception secondary to BL indexed in MEDLINE (PubMed) [ 28 ]–[ 39 ]. The features of these cases are summarized in Table 1 .…”

Section: Discussionmentioning

confidence: 99%

Burkitt Lymphoma Presenting as Ileocolic Intussusception in an Adult

Borré,

Boyle,

Lynch

et al. 2023

OJBD

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Adult intussusception is rare, highly associated with a malignant lead point, and often requires emergent surgical management. We report the case of a 44-year-old male who presented with generalized abdominal pain and was found to have early ileocolic intussusception secondary to a large ileocecal mass. Biopsies of the mass and an enlarged cardiophrenic lymph node, as well as pleural fluid cytology were all consistent with Burkitt lymphoma (BL). Curiously, the patient's abdominal exam was reassuring, and the intussusception and malignant bowel obstruction resolved over 36 hours with conservative management alone. With a Burkitt lymphoma international prognostic index (BL-IPI) score of 2, the patient proceeded to treatment with combination chemoimmunotherapy and attained a complete response after four cycles. There was no bowel perforation or recurrent intussusception throughout treatment. Thus, this report marks the first reported case of adult BL-associated intussusception to resolve with non-invasive management and establishes a precedent for conservative management in select patients.

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“…We identified 12 prior reports of adult intussusception secondary to BL indexed in MEDLINE (PubMed) [ 28 ]–[ 39 ]. The features of these cases are summarized in Table 1 .…”

Section: Discussionmentioning

confidence: 99%

Burkitt Lymphoma Presenting as Ileocolic Intussusception in an Adult

Borré,

Boyle,

Lynch

et al. 2023

OJBD

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“…62 Acute renal failure secondary to hydronephrosis, tumor lysis syndrome, due to the hasty cell turnover, 40 and intussusceptions (obstruction of the intestine) are the most common clinical presentation. 63 In terms of stage, extra-nodal involvement, and histology, patients with HIV-BL match the general BL population. 64 Epidemiology BL is the second commonest subtype next to DLBCL and covers 25-40% of HIV-associated NHL.…”

Section: Aids Related Burkitt Lymphomamentioning

confidence: 99%

Human Immunodeficiency Virus Related Non-Hodgkin’s Lymphoma

Gessese¹,

Asrie²,

Mulatie³

2023

BLCTT

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Human immunodeficiency virus infection is related with an increased risk of hematological malignancy principally, non-Hodgkin lymphoma. Most non-Hodgkin lymphomas are acquired immunodeficiency syndrome defining and constitute greater than 50% of all acquired immunodeficiency syndrome defining cancers. The main pathogenesis mechanisms are immunodeficiency, chronic antigenic stimulation, and the ability to infect cancer cells causing direct carcinogenesis. Human immunodeficiency virus related non-Hodgkin lymphomas are heterogeneous in immunophenotyping and molecular features; and choice of drug treatments is similar with sporadic types. The main objective is to assess the epidemiology, pathogenesis, and morphology of human immunodeficiency virus related non-Hodgkin lymphoma. The searching strategy was done by searching relevant original and review articles from www.biosemanticjane/org, Google scholar, Google, and PubMed sites using keywords like; Acquired immunodeficiency syndrome, Human immunodeficiency virus, and non-Hodgkin lymphoma. In conclusion, human immunodeficiency virus infected people continue to have elevated risk of non-Hodgkin lymphoma. Diffuse large B-cell lymphomas are the most common and severe subtype. The pathogenesis of this type of lymphoma is associated with chromosomal abnormalities that deregulate the expression of various oncogenes by different viral particles and cytokines. However, the role of these viral particles and cytokines on pathogenesis is not clearly stated, so further study could be required.

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“…2 BL stands for 9% of the cases of primary small intestine lymphoma and clinical presentations includes intestinal obstruction or intussusception, small bowel perforation or as an incidental finding. [1][2][3][4][5][6][7] We presented a case of intestinal obstruction by the form of ileum to cecum intussusception secondary to a Burkitt's lymphoma in a middle-aged man with signs of microperforation. platelet count.…”

Section: Introductionmentioning

confidence: 99%

Adult Burkitt's lymphoma presenting as ileocecal intussusception

Ferreira

Clara²,

Pais³

et al. 2023

Int Surg J

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Most lymphomas of gastrointestinal tract arise mainly in stomach but can affect small bowel. Burkitt’s lymphoma stands for 9% of the cases of primary small intestine lymphoma and clinical presentations may vary. Case report of a 58-years old man presenting an acute abdomen secondary to intestinal obstruction with tomography revealing an ileocecal mass suspicious for intussusception. Surgery was performed and an invaginating mass from ileum-to-cecum lead to a laparoscopic right colectomy. Histopathological analysis established the diagnosis of ileocecal Burkitt’s lymphoma. Post-operative period was uneventful and the patient was referred to oncohematology and started early chemotherapy. Clinical situations of intestinal intussusception or small-bowel masses presenting with obstruction should rise the suspicion for malignancy and the surgeon must be aware of this clinical entity to proceed with an oncologically safe surgery. Intestinal perforation may indicates surgery as it leads to peritoneal tumor spread and indicates a worse prognosis. Laparoscopic surgery approaches must be seriously considered in selected cases. In intestinal lymphoma, early refer to oncohematology for evaluation and treatment is essential and establishes a better prognosis.

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A Case of Jejunal Intussusception caused by Burkitt Lymphoma in an Acquired Immunodeficiency Syndrome Patient

Cited by 4 publications

References 16 publications

Burkitt Lymphoma Presenting as Ileocolic Intussusception in an Adult

Burkitt Lymphoma Presenting as Ileocolic Intussusception in an Adult

Human Immunodeficiency Virus Related Non-Hodgkin’s Lymphoma

Adult Burkitt's lymphoma presenting as ileocecal intussusception

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