“…There are 24 reported cases of colonic adenocarcinima seeding into anal fistula [4] , [13] , [14] , [15] , [16] , [17] , [18] , [19] , [20] , [21] , [22] , [23] , [24] , [25] and the vast majority of cases regard male patients [5] . Marker as CK20 and CK7 can be useful in distinguishing the original from the metastatic carcinoma as the literature reports [4] , [5] .…”