A case of multiple synostoses syndrome

High risk factors for craniosynostosis during pregnancy: A case-control study

“…In that case, the mother’s infant 17a-hydroxyprogesterone intake for abortion was considered unrelated to the CS [19] . In another case of multiple synostoses, including CS, the mother was treated with progesterone injections for atypical genital bleeding [20] . Andley-Bixler syndrome is an entity that encompasses CS and is associated with impaired steroid synthesis and FGFR mutations, whilst some cases possibly have P450 oxidoreductase deficiency and elevation of 17-OH-progesterone levels with normal basal cortisol levels [21] .…”