2015
DOI: 10.4103/1817-1737.152461
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A case of near fatal asthma: The role of ECMO as rescue therapy

Abstract: We report a case of an adolescent with near fatal asthma (NFA). He presented with severe hypoxemia and lifethreatening acidemia, who failed to respond to conventional therapy. His hospital course was complicated by barotrauma and hemodynamic instability. Early introduction of extracorporeal membrane oxygenation (ECMO) led to dramatic improvement in gas exchange and lung mechanics. This case illustrates the important role of ECMO as salvage therapy in NFA.

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Cited by 18 publications
(12 citation statements)
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“…Hence, an aggressive management approach and continuous monitoring are mandatory. [ 219 ] The following steps are recommended for further management:…”
Section: Methodsmentioning
confidence: 99%
“…Hence, an aggressive management approach and continuous monitoring are mandatory. [ 219 ] The following steps are recommended for further management:…”
Section: Methodsmentioning
confidence: 99%
“…Hence, an aggressive management approach and continuous monitoring are mandatory. [245] The following steps are recommended for further management: Consult ICU service. Intubation setting should be readily availableAdequate oxygen flow to keep saturation ≥92%[225]Deliver continuous nebulized salbutamol at a dose of 10–15 mg with ipratropium bromide at a dose of 1.5 mg over 1 h (Evidence A).…”
Section: Management Of Acute Asthma In Adults and Adolescentsmentioning
confidence: 99%
“…Hence, an aggressive management approach and continuous monitoring are mandatory. [245] The following steps are recommended for further management:…”
Section: Management Of Acute Asthma In Adults and Adolescentsmentioning
confidence: 99%
“…Extracorporeal membrane oxygenation (ECMO) is an invasive therapy, in which oxygenation and carbon dioxide removal are performed through an artificial membrane. Although evidence based on clinical trials for the use of ECMO in asthmatic patients is lacking [277,278], there is growing evidence on the subject, supporting the use of ECLS for patients receiving mechanical ventilation due to an asthmatic exacerbation. A 2009 review by Mikkelsen et al has demonstrated that, when ECLS is used for status asthmaticus, it correlates with better outcomes in comparison to its use for other causes of respiratory failure [279].…”
Section: Pharmacological and Non-pharmacological Managementmentioning
confidence: 99%