A case of normotensive incidentally discovered adrenal pheochromocytoma

Ohara, Nobumasa; Kaneko, Masanori; Yaguchi, Yuta; Ishiguro, Hajime; Ishizaki, Fumio; Maruyama, Ryo; Suzuki, Kazuya; Komeyama, Takeshi; Usuda, Hiroyuki; Yamazaki, Yuto; Sasano, Hironobu; Kaneko, Kenzo; Kamoi, Kyuzi

doi:10.1002/ccr3.1772

Cited by 5 publications

(3 citation statements)

References 20 publications

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“…Clinical symptoms, such as increased blood pressure, palpitations, headache, sweating, and tremors, may be paroxysmal [30]. They are characteristic; however in some cases may not occur [31]. Due to possible complications, especially caused by hypertension, the suspicion of PHEO is an indication for adrenalectomy preceded by α 1 -adrenoreceptor antagonist preparation.…”

Section: Discussionmentioning

confidence: 99%

Adrenal Tumors in Young Adults: Case Reports and Literature Review

Zdrojewska

Mech-Siebieszuk

Świątkowska−Stodulska

et al. 2022

Medicina

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The current high detection rate of adrenal tumors (4–10% of general population) is attributable to a widespread use of variety of imaging studies, especially a computed tomography. Most of them represent clinically silent and biologically indolent incidentalomas, but some adrenal tumors may pose a significant clinical challenge. Thus, in every patient with an adrenal tumor, a decision on further management is made after careful hormonal and radiological evaluation. All hormonally active tumors and those with radiological features suggesting malignancy are qualified for surgery. Approximately 80% of adrenal tumors are adrenocortical adenomas, hypertrophy, or nodular adrenocortical hyperplasia. Other histopathological diagnoses include pheochromocytoma, adrenocortical carcinoma, metastases, mesenchymal tumors, lymphomas, cysts, and ganglioneuromas. Adrenal tumors are more commonly diagnosed and better studied in elderly patients. In younger patients, under 40 years old, focal adrenal lesions are relatively rare, and histological distribution of diagnoses differs from that in elderly individuals. Younger patients are more likely to display endocrine symptoms, which raise the suspicion of an adrenal mass. In the current study, we present a case series of seven adrenal tumors occurring in young patients. The cases presented below, along with the literature review, demonstrate that the diagnosis and treatment of adrenal tumors are crucial due to endocrinopathy-derived complications and a potential risk of malignancy.

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Section: Discussionmentioning

confidence: 99%

Adrenal Tumors in Young Adults: Case Reports and Literature Review

Zdrojewska

Mech-Siebieszuk

Świątkowska−Stodulska

et al. 2022

Medicina

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“…PPGL patients' anesthesia management is very challenging. First, preoperative preparation should be adequate, such as the use of αblockers and augmentation of blood volume [15,16]. Second, hemodynamic monitoring during the surgery is essential.…”

Section: Discussionmentioning

confidence: 99%

A case of an unexpected posterior mediastinal functional paraganglioma: case report and literature review

2020

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Background: Paraganglioma can be found in a wide range of locations. However, paraganglioma in the posterior mediastinum is rare. An unexpected paraganglioma located in the posterior mediastinum was found during surgery. The anesthesia management of this patient was challenging. Case presentation: A 65-year-old male with a posterior mediastinal tumor was scheduled for thoracoscopic mediastinal tumor resection. Severe hemodynamic changes during the operation and postoperative pathological diagnosis showed that the patient had a rare case of posterior mediastinal functional paraganglioma, which was not found before the operation. Although the patient did not experience side effects after surgery, he did experience a dangerous surgical process. Conclusions: The correct diagnosis of paraganglioma, intensive preoperative screening, adequate preoperative preparation, and accurate intraoperative anesthesia management could provide better anesthesia for paraganglioma patients.

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“…The method of measurement for plasma and urinary catecholamines and metanephrines was mentioned only in eight studies, either as high performance liquid chromatography ( 9 , 29 , 58 , 59 , 63 ) or liquid chromatography with mass spectrometry ( 23 , 61 , 86 ).…”

Section: Overview Of the Literaturementioning

confidence: 99%

Silent pheochromocytoma and paraganglioma: Systematic review and proposed definitions for standardized terminology

et al. 2022

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Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors with heterogeneous clinical presentations and potential lethal outcomes. The diagnosis is based on clinical suspicion, biochemical testing, imaging and histopathological confirmation. Increasingly widespread use of imaging studies and surveillance of patients at risk of PPGL due to a hereditary background or a previous tumor is leading to the diagnosis of these tumors at an early stage. This has resulted in an increasing use of the term “silent” PPGL. This term and other variants are now commonly found in the literature without any clear or unified definition. Among the various terms, “clinically silent” is often used to describe the lack of signs and symptoms associated with catecholamine excess. Confusion arises when these and other terms are used to define the tumors according to their ability to synthesize and/or release catecholamines in relation to biochemical test results. In such cases the term “silent” and other variants are often inappropriately and misleadingly used. In the present analysis we provide an overview of the literature and propose standardized terminology in an attempt at harmonization to facilitate scientific communication.

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A case of normotensive incidentally discovered adrenal pheochromocytoma

Cited by 5 publications

References 20 publications

Adrenal Tumors in Young Adults: Case Reports and Literature Review

Adrenal Tumors in Young Adults: Case Reports and Literature Review

A case of an unexpected posterior mediastinal functional paraganglioma: case report and literature review

Silent pheochromocytoma and paraganglioma: Systematic review and proposed definitions for standardized terminology

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