2003
DOI: 10.1136/jnnp.74.6.825
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A case of possible autoimmune bilateral vestibulopathy treated with steroids

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Cited by 37 publications
(19 citation statements)
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“…In a study investigating sera from patients with bilateral idiopathic vestibular failure (BIVF), the majority of sera were shown to contain antibodies mainly against the ampullary tissue and the semicircular canals [23]. The same group of researchers has, in a recent case report [24] on a patient with possible autoimmune bilateral vestibulopathy, confirmed the presence of autoantibodies against the vestibular parts of the inner ear. Interestingly, after treatment with steroids a complete recovery of vestibular function was seen in this patient, and the recovery correlated with the disappearance of serum autoantibodies against vestibular tissues.…”
Section: Pathogenesismentioning
confidence: 81%
See 1 more Smart Citation
“…In a study investigating sera from patients with bilateral idiopathic vestibular failure (BIVF), the majority of sera were shown to contain antibodies mainly against the ampullary tissue and the semicircular canals [23]. The same group of researchers has, in a recent case report [24] on a patient with possible autoimmune bilateral vestibulopathy, confirmed the presence of autoantibodies against the vestibular parts of the inner ear. Interestingly, after treatment with steroids a complete recovery of vestibular function was seen in this patient, and the recovery correlated with the disappearance of serum autoantibodies against vestibular tissues.…”
Section: Pathogenesismentioning
confidence: 81%
“…No concordance in terms of auditory and vestibular pathology has been shown. Accordingly, audiological and vestibular symptoms may appear isolated or combined, with symptoms resembling Meniè re's disease [2,24,28,29]. Meniè re's disease-like symptoms due to immunemediated inner-ear disorders often affect both ears simultaneously, causing asymmetrical bilateral audiovestibular dysfunction.…”
Section: Clinical Presentationmentioning
confidence: 99%
“…In contrast, central disorders [e.g., spinocerebellar degeneration (2), meningeal carcinomatosis (3), or meningitis (4) -edema and anti-inflammatory (1, 6, 7). Recently, autoimmune bilateral vestibulopathy has been reported (8). It usually occurs together with sensory deafness (9), but may precede sensory deafness or occur alone (8,9 …”
Section: Introductionmentioning
confidence: 99%
“…Recently, autoimmune bilateral vestibulopathy has been reported (8). It usually occurs together with sensory deafness (9), but may precede sensory deafness or occur alone (8,9 …”
Section: Introductionmentioning
confidence: 99%
“…Compensatory spontaneous healing seldom occurs. Systemic application of ototoxic drugs, trauma, neurological problems such as migraine, multiple sclerosis, bilateral inner ear problems such as cochlear otosclerosis, immune mediated inner ear disease, bilateral Meniere's syndrome, and congenital abnormalities such as large vestibular aqueduct syndrome may cause gradual or sudden bilateral loss of vestibular function [2] . Bilateral cochleovestibulopathy due to bilateral metastasis of the internal auditory canal (IAC) is extremely rare.…”
Section: Introductionmentioning
confidence: 99%