A case of recurrent toxin-mediated perineal erythema

Bouch, Rachida El; Reubsaet, Pauline; Koop, Klaas; Jansen, Jurgen

doi:10.1136/archdischild-2013-304564

Cited by 4 publications

(3 citation statements)

References 5 publications

(1 reference statement)

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“…Recurrent toxin‐mediated perineal erythema (RTPE) is a benign self‐limiting disorder caused by staphylococcal and streptococcal exotoxins acting as superantigens. Unlike usual antigens which are processed inside antigen‐presenting cells, superantigens bypass this step and bind directly to the MHCII complex molecules and T‐cell receptors inducing polyclonal B‐cell activation, nonspecific T‐cell proliferation, and massive proinflammatory cytokine production 1‐4 . RTPE is more frequent in young children under the age of 12, but adults may occasionally be affected.…”

Section: Discussionmentioning

confidence: 99%

“…Accompanying signs include acral desquamation and mucosal changes such as strawberry tongue. The patient is generally well, and systemic symptoms, such as fever, are uncommon 1,3 …”

Section: Discussionmentioning

confidence: 99%

“…Systemic amoxicillin therapy typically results in a quick resolution of symptoms, generally without sequelae. If relapses are frequent, tonsillectomy should be considered 3 …”

Section: Discussionmentioning

confidence: 99%

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A peculiar perineal erythema

Altobrando

Baccelli

Virdi

et al. 2020

Pediatric Dermatology

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Section: Discussionmentioning

confidence: 99%

“…Accompanying signs include acral desquamation and mucosal changes such as strawberry tongue. The patient is generally well, and systemic symptoms, such as fever, are uncommon 1,3 …”

Section: Discussionmentioning

confidence: 99%

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A peculiar perineal erythema

Altobrando

Baccelli

Virdi

et al. 2020

Pediatric Dermatology

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Bacterial Infections

Hay,

Morris‐Jones

2016

Rook's Textbook of Dermatology, Ninth Edition

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This chapter starts by considering the resident bacterial population of the skin and how this has altered with our growing understanding of the skin microbiome. It then reviews the whole range of bacterial skin infections from primary Gram‐positive infections due to staphylococci and streptococci to the less common infections caused by Gram‐negative and anaerobic bacteria. The cutaneous manifestations of common and rare systemic bacterial infections such as staphylococcal septicaemia and melioidosis are described in practical detail. Using new work on antibiotics, the spread of drug resistance amongst skin bacterial pathogens is reviewed and its relevance clarified in the treatment algorithms. Rickettsial infections are also considered.

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Bacterial Infections

Wootton,

Elliott

2024

Rook's Textbook of Dermatology

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The skin provides a barrier between the body and the external environment and it is colonised by the bacteria and other microorganisms that make up the skin microbiome. Bacterial infections occur when bacteria invade through damage to the skin barrier, via trauma or pre‐existing skin conditions, or through inoculation or inhalation; bacterial skin infections can range from minor irritations to life‐threatening conditions. This chapter explores bacterial infections which can affect the skin, from the common to the rare, describing the epidemiology, presentation and management of each condition.

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A case of recurrent toxin-mediated perineal erythema

Cited by 4 publications

References 5 publications

A peculiar perineal erythema

A peculiar perineal erythema

Bacterial Infections

Bacterial Infections

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