A Case of Ruptured Gastrointestinal Stromal Tumor in the Stomach with Intraabdominal Hemorrhagic Shock.

Hirata, Ken Ichi; Yano, Yuka; Inokuchi, Toshihiro; Kuga, Takayuki; Fujii, Yasuhiro; Nishimura, Junichi; Yamaguchi, Yuki; Mitani, Noriyuki; Nagadomi, Yuji

doi:10.2342/ymj.65.137

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“…Eighty percent of ruptured GISTs developed in small bowel and 11% in stomach [ 2 ]. More than 5 cm in diameter has been reported as one of the risk factors for rupture [ 22 ]. Ruptured gastric GIST can usually present with occult bleeding, so a life-threatening bleeding is rare at 1% [ 23 ].…”

Section: Discussionmentioning

confidence: 99%

Coexistence of gastric cancer and gastric GIST with intra-tumor bleeding: successful embolization with subsequent total gastrectomy

et al. 2021

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Background Gastrointestinal stromal tumor (GIST) is a rare tumor, however, simultaneous development of gastric cancer and gastric GIST has been documented more frequently in recent years. Rupture of gastric GIST is even more rare and occurred in 7% of all GISTs. Although ruptured GIST might be occasionally difficult to be managed by endoscopy, transcatheter arterial embolization (TAE) was reported to control bleeding from GIST effectively. We report herein a case of coexistence of gastric cancer and gastric GIST with progressing intra-tumor bleeding managed successfully by TAE and review the clinicopathological characteristics of this rare condition reported previously in the Japanese literature. Case presentation A 75-year-old woman with dyspnea and systemic edema was diagnosed as simultaneous occurrence of gastric cancer (histopathologically detected tubular adenocarcinoma pT2N1M0 fStageIIA) and gastric GIST (65 × 92 mm in diameter at the anterior wall of the fornix) with intra-tumor hemorrhage. Perceiving the progress of bleeding from tumor growth and exacerbating anemia, TAE of left gastric artery was performed. Then remission of anemia has been obtained, the patient underwent an elective radical surgery. Conclusions Simultaneous occurrence of gastric cancer and gastric GIST was speculated to be more common. TAE for ruptured GIST may be effective for hemostasis and reduction of tumor burden, which could facilitate minimal invasive surgery.

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Section: Discussionmentioning

confidence: 99%