A Case Report: Hallermann-Streiff Syndrome

Abstract

Hallermann-Streiff is a rare syndrome characterized by multiple congenital anomalies, especially in the head and face. It was first described by Hallermann in 1948 and later by Streiff in 1950. Patients have a bird-like face, skin atrophy, dwarfism, various eye abnormalities, and hypotrichosis. In the case admitted to our hospital with complaints of fever, cough, and failure to thrive, we detected microphthalmia, bilateral leukocoria, cataract, eyebrow hypotrichosis, a prominent nose, and depressed nasal root. The patient was diagnosed with Hallermann-Streiff syndrome. This case was presented because of its rare occurrence in the literature.

Pediatric difficult intubation in a rare genetic disorder made easy with Airtraq laryngoscope

“…The etiology remains an enigma; although sporadic mutation is considered in majority of the patients, there is an association in literature with consanguinity, antenatal rubella infection, and familial medical history. [ 1 ] We report a case of 12-year-old male child, a product of nonconsanguineous marriage, postrubella syndrome (echocardiography normal), born preterm (32 weeks of gestation), planned for urethroplasty. Anthropometry revealed weight of 23 kg (<3 rd percentile), height of 128 cm (<3 rd percentile), and occipital-frontal circumference of 50 cm (<3 rd percentile), and karyotyping was normal.…”