A case report of hepatic abscesses due to yersinia enterocolitica associated with hemosiderosis.

Kitayama, Joji; Osada, Takuya; Hamaguchi, Masaaki; Kobayashi, Ryo; Ohi, Toshitaka; Inden, Yasuyuki; Hara, Kosuke; Tomiyama, J; Ichikawa, Noritoshi; Tsukui, Hajime; Itoyama, Shinji

doi:10.5833/jjgs.21.2603

Cited by 2 publications

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“…The impairment of the ceruloplasmin function causes iron overload in several organs, including the liver, pancreas and brain ( 11 ). Hepatic yersiniosis and hepatic hemosiderosis, which had been diagnosed when our patient was 37 years of age ( 12 ), were retrospectively determined to have been caused by aceruloplasminemia. Because aceruloplasminemia is frequently associated with anemia due to defective iron utilization ( 13 ), it is possible that the patient's hyporesponsiveness to ESA was caused by defective iron utilization due to aceruloplasminemia.…”

Section: Discussionmentioning

confidence: 99%

The Resection of Thyroid Cancer Was Associated with the Resolution of Hyporesponsiveness to an Erythropoiesis-stimulating Agent in a Hemodialysis Patient with Aceruloplasminemia

et al. 2017

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We herein report the case of a hemodialysis patient whose response to an erythropoiesis-stimulating agent (ESA) improved following the resection of thyroid cancer. Her hemoglobin level remained below 7 g/dL, despite the use of ESA. During the search for the causes of her hyporesponsiveness to ESA, papillary thyroid cancer and aceruloplasminemia were found. The existence of other potential causes, such as iron deficiency, infectious disease, severe hyperparathyroidism and malnutrition were ruled out. Following the resection of the thyroid cancer tumor, her hemoglobin level increased to 10.2 g/dL over a period of 4 months. This is the first report to demonstrate the resolution of hyporesponsiveness to ESA following the resection of a malignant tumor.

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Section: Discussionmentioning

confidence: 99%

The Resection of Thyroid Cancer Was Associated with the Resolution of Hyporesponsiveness to an Erythropoiesis-stimulating Agent in a Hemodialysis Patient with Aceruloplasminemia

et al. 2017

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“…Twenty-three cases had multiple liver abscesses and five cases had solitary abscess. Seven cases had reported CT scan of the liver, two cases revealed a solitary mass (17,28) and five cases showed multiple small low density areas throughout the liver parenchyma (20,22,24,29,30). In the cases of multiple abscesses, they appear as multiple small sized areas like cysts and metastasis.…”

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confidence: 99%

“…Leukemia, diabetes mellitus, liver cirrhosis, administration of immunosuppressive drugs and renal failure with peritoneal dialysis have been reported as a complication of sepsis (3). (24,30). The age range was 37-75 years old (average 57.1 ± 12.6 S.D.…”

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Multiple Liver Abscesses Secondary to Yersinia Enterocolitica.

et al. 1992

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A 37-year-old male, a poorly-controlled insulin-dependent diabetic patient, was admitted to our hospital with complaints of high fever and confusion. Laboratory data showed hyper glycemia, positive inflammatory reaction and liver dysfunction. Blood culture demonstrated Yersinia enterocolitica. Liver CT scan showed multiple low density areas. These data were consistent with a diagnosis of liver abscess secondary to Yersinia enterocolitica. He died of disseminated intravascular coagulation; subsequent autopsy confirmed the clinical diagnosis. Liver abscess secondary to Yersinia enterocolitica with septicemia is rare, but has been reported in compromised hosts. In the mechanism of this disease, the alimentary tract has been suggested to be the port of entry in most cases. (Internal Medicine 31: 1125-1127, 1992 Key words: sepsis, diabetes mellitus, serotype 03 antibody, hepatic encephalopathy Intr oductionWe treated a case of sepsis and multiple liver ab scesses due to Yersinia enterocolitica (Y.E) in an insulin dependent diabetes mellitus patient. In Japan, it is rare to find severe infection caused by Y.E., especially in adult patients. Case ReportA 37-year-old diabetic man was treated with insulin for ten years, but his diabetic condition was not well controlled. On September 27, 1986, he began to suffer from high fever and diarrhea; nausea, vomiting and mild disturbance of consciousness later developed, and he was admitted to our hospital on November 7, 1986. On admission, BP was 94/70 mmHg, body temperature was 37.4°C, and consciousness was confused. The patient's skin was dry; there were no other abnormal findings on physical examination.Laboratory data showed WBC 5800/mm3 (Band 3, Seg (Fig. 1) showed multiple round low density areas (2-5cm in diameter) in the bilateral lobes of the liver. Ultrasound also showed multiple clear margins around hypoechoic lesions. These data suggested liver abscesses secondary to Y.E. with septicemia. Chemo therapy was started with ceftizoxime (CZX) 6g/day; piperacillin (PIPC) 4 g/day was later added. Neurological signs (flapping tremor, confusion and dyscalculia) were thought to be caused by hepatic encephalopathy. Lactulose and aminoleban were administrated, and the patient's serum ammonia level decreased, but the disturbance of consciousness did not show any improvement. Spike fever continued and serum albumin decreased to 0.9 g/dl.Generalized edema, pulmonary effusion, ascites and jaundice developed. Diuretics and frozen fresh plasma were administered, but hypoalbuminemia, generalized edema, and pulmonary effusion failed to improve. On the 17th day after admission, gastrointestinal bleeding occured. He died of disseminated intravascular coagu lation (DIC) and pulmonary edema on the 29th day after admission.

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A case report of hepatic abscesses due to yersinia enterocolitica associated with hemosiderosis.

Cited by 2 publications

References 0 publications

The Resection of Thyroid Cancer Was Associated with the Resolution of Hyporesponsiveness to an Erythropoiesis-stimulating Agent in a Hemodialysis Patient with Aceruloplasminemia

The Resection of Thyroid Cancer Was Associated with the Resolution of Hyporesponsiveness to an Erythropoiesis-stimulating Agent in a Hemodialysis Patient with Aceruloplasminemia

Multiple Liver Abscesses Secondary to Yersinia Enterocolitica.

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