A Case Report of Priapism With Unusual Presentation and Clinical Course

Abstract

This is a case report on a patient with an unusual presentation and clinical course of priapism. It further discusses treatment options with reflection on current literatures and guidelines. 48 year old patient presented with a history of more than 50 episodes of priapism, each lasting for five minutes. Patient had history of brain tumor that was resected and had since been in remission. On examination and further biochemistry assessment revealed conflicting clinical findings, making it difficult to ascertain the type of priapism in this case. The patient, however, recovered from the acute attacks of priapism after 24 hours of conservative management and no obvious cause had been identified on post-discharge follow-up. Priapism, despite being rare, is a medical emergency. This case report reflected upon the limitations of treatment guidelines and the lack of level one evidence to support treatment decisions.

Establishment of mouse line showing inducible priapism‐like phenotypes

“…Patients with spinal cord lesions or neurodegenerative diseases occasionally suffer from priapism. 56 , 57 , 58 Pitpna ‐deficient mice are born alive and exhibit spinocerebellar neurodegenerative disease. They die from multiple systemic disorders within a few days of birth.…”

“…These results imply that PI may contribute to penile erection by PITPα. Patients with spinal cord lesions or neurodegenerative diseases occasionally suffer from priapism 56–58 . Pitpna ‐deficient mice are born alive and exhibit spinocerebellar neurodegenerative disease.…”