2018
DOI: 10.1186/s40249-018-0411-x
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A case report of spontaneous abortion caused by Brucella melitensis biovar 3

Abstract: BackgroundBrucellosis is a worldwide zoonotic disease caused by Brucella spp. Brucella invades the body through the skin mucosa, digestive tract, and respiratory tract. However, only a few studies on human spontaneous abortion attributable to Brucella have been reported. In this work, the patient living in Shanxi Province in China who had suffered a spontaneous abortion was underwent pathogen detection and Brucella melitensis biovar 3 was identified.Case presentationThe patient in this study was 22 years old. … Show more

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Cited by 16 publications
(14 citation statements)
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“…In line with this, several reports suggested the combination therapy of doxycycline and rifampicin for six weeks is enough to eradicate Brucella infection, as well as associated complications [ 46 , 109 , 110 , 111 ]. This combination of doxycycline and rifampicin has also been proven experimentally [ 112 ]. As a result of continued efforts by the scientific community to develop an effective therapeutics, Caryopteris mongolica Bunge (Lamiaceae) has been tested in combination with doxycycline [ 113 , 114 ].…”
Section: Treatment Of Brucellosismentioning
confidence: 99%
“…In line with this, several reports suggested the combination therapy of doxycycline and rifampicin for six weeks is enough to eradicate Brucella infection, as well as associated complications [ 46 , 109 , 110 , 111 ]. This combination of doxycycline and rifampicin has also been proven experimentally [ 112 ]. As a result of continued efforts by the scientific community to develop an effective therapeutics, Caryopteris mongolica Bunge (Lamiaceae) has been tested in combination with doxycycline [ 113 , 114 ].…”
Section: Treatment Of Brucellosismentioning
confidence: 99%
“…Relevant sequences were deposited in the GenBank database (omp22: M H 3 1 6 1 6 8 a n d M H 3 1 6 1 6 9 ; I S 7 1 1 : MH316166 and MH316167). According to PCR and sequencing results, the procedures of classical Brucella isolation and phenotypic identification were conducted (Yang et al 2018). Briefly, the livers and spleens from 10 Brucella DNA-positive marmots were respectively homogenized, then their suspensions were individually inoculated onto Brucellaselective agar plates (Becton, Dickinson and Company, Sparke, Maryland, USA).…”
mentioning
confidence: 99%
“…After incubation at 37°C and 5% CO 2 atmosphere for 3–5 days (blind passage for more 3–5 days of cultivation may be needed), the Brucella suspicious bacteria strain was streaked on both a blood agar plate and a Brucella agar plate for further identification. Traditional biological methods including colony morphology, Gram stain, CO 2 requirements, H 2 S production, agglutination with monospecific antisera, and phage lysis test, were used for the identification of the Brucella suspicious bacterial isolates (Yang et al, 2018). Simultaneously, genomic templates from the 156 whole blood samples were extracted using protocol of QIAamp.…”
Section: Methodsmentioning
confidence: 99%