A Case Report on Steroid Induced Acneiform Eruptions

Abstract

Acne is the chronic inflammatory disease of the pilosebaceous unit, characterized by the formation of comedones, erythematous papules and pustules shortly after starting topical or oral corticosteroid. We report a case of acneiform eruptions on a Eosinophilic gastroenteritis (EGE) patient who was treated with prednisolone 30 mg 1-0-0, 2 weeks, three months ago. She developed pustular rashes over the face and back on and off during past 3 months. Presently she got admitted in the gastroenterology department for reoccurence of the symptoms associated with EGE and treated with prednisolone 30 mg 1-0-0. Dermatology opinion was sought for the aggravated pustular rashes over the face and back confirmed to be prednisolone induced acneiform eruptions. Following which, prednisolone was withdrawn within 48 h of admission and treated symptomatically with Clindamycin 1% gel.

Successful alopecia universalis treatment with the combination of cyclosporine and oral corticosteroid: a case report

“…The most important treatment step is identifying the causing drug and stopping treatment. 30,31 In this case, the patient was given 2% topical sulfur every 12 hours on acneiform eruption lesions. The patient did not find other side effects from steroids, such as striae, obesity, cataract, and hypertension.…”

Erupsi Akneiformis dan Striae Distensiae setelah Terapi Kortikosteroid Sistemik untuk Nefritis Purpura Henoch-Schonlein

“…Kortikosteroid sistemik ataupun topikal merupakan penyebab ketiga terbanyak (14,6%). 8 Reaksi simpang akibat pemberian kortikosteroid tergantung dosis dan lama pemberian serta kerentanan individu. Pemberian kortikosteroid sistemik terus-menerus mulai dari 2 minggu lebih dapat mencetuskan EA.…”

“…4,7 Patogenesis EA sepenuhnya belum diketahui pasti, salah satunya karena efek langsung pada epitel folikuler, yaitu degenerasi fokal dengan inflamasi netrofilik intrafolikuler dan perifolikuler terlokalisata. 8 Obat-obatan selain kortikosteroid yang dapat menimbulkan EA antara lain androgen, lithium, kontrasepsi oral, obat kemoterapi, iodin, bromide, isoniazide, actinomycin D, phenytoin dan belakangan ini dilaporkan akibat suplementasi mengandung susu dan whey protein. 6 Penatalaksanaan kasus ini sesuai kepustakaan bahwa penghentian konsumsi obatobatan yang dicurigai menginduksi EA merupakan yang utama.…”