A case series on Covid-19 infection and avascular necrosis of hip

Jyothiprasanth, M.; R, Jithin C.; Vincent, Anita; Thomas, Akhil K.; Pratheesh, C.B.; Sarang, P

doi:10.1016/j.jorep.2022.100104

Cited by 9 publications

(11 citation statements)

References 7 publications

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“…Cases of aseptic and bacterial osteonecrosis involving hipbone, femur, and vertebrae were reported as early as within a few weeks of COVID-19 [ 4 , 5 ]. In, the maxillofacial skeleton such cases were reported as early as 8 days after COVID-19 [ 7 ].…”

Section: Discussionmentioning

confidence: 99%

“…The COVID-19 pandemic was an unprecedented infection the aftereffects of which are still being reported with complications involving all the major systems of the human body [ [1] , [2] , [3] ]. Cases of osteonecrosis of the maxilla and mandible are being reported with an increased frequency apart from that involving the femur, vertebrae, and hipbones [ 4 , 5 ]. Recently, Al-Mahalawy et al reported a case series of maxillary osteonecrosis in 12 diabetic patients in a multicentric study [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

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Is post-COVID osteonecrosis of jaw (PCONJ) Masquerading as osteomyelitis ? A largest unicentric report of 13 cases

Khan¹,

Rahman²,

Rahman³

et al. 2023

Advances in Oral and Maxillofacial Surgery

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Is post-COVID osteonecrosis of jaw (PCONJ) Masquerading as osteomyelitis ? A largest unicentric report of 13 cases

Khan¹,

Rahman²,

Rahman³

et al. 2023

Advances in Oral and Maxillofacial Surgery

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“…The treatment for moderate to severe cases is consisted of antiviral therapy and corticosteroids, which could be administered either intravenously, either oraly. Three studies combined the antiviral medication with steroids (12)(17)( 22), while at the same time three other studied, did not use any corticosteroid (18) (19) (25). However, Veizi et al (7), divided the patients into two groups and half of them were treated with steroid and the rest, without.…”

Section: Covid-19 Treatmentmentioning

confidence: 99%

A Comprehensive Review of COVID-19 Infection and Steroid-Associated Treatment Bone Avascular Necrosis: A Multi-Study Analysis

Sakellariou,

Argyropoulou,

Karampinas

et al. 2023

Preprint

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Background: The COVID-19 pandemic has presented numerous challenges to global healthcare system and emerging evidence suggests a potential link between COVID-19 treatment, specifically steroid therapy, and the development of avascular necrosis (AVN) of the hip. This review aims to provide a comprehensive overview of recent studies and case reports investigating the relationship between COVID-19, corticosteroid therapy, and the development of AVN. Understanding the nuances of AVN in the context of COVID-19 is crucial for healthcare professionals to navigate treatment decisions and mitigate potential complications. Materials and Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) was used in the systematic review until September 1st, 2023. The full-texts of the remaining twenty-three (n=23) articles were independently reviewed by the authors of this review. Conclusions: The association between steroid therapy for COVID-19 and the development of hip AVN is a noteworthy concern even though, no relationship is evident between the duration of treatment, cumulative dosage of medication, maximum daily dosage received, and the presence of AVN. Further research with larger cohorts and long-term follow-up is needed to better understand the causative relationship and optimal management strategies for hip AVN in the context of COVID-19 and steroid therapy

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“…The relationship between osteonecrosis and COVID has been described in the literature, referring to a multitude of joints, with the femoral head being the most frequently mentioned 9 . However, other joints such as the jaw, humeral head, knee, talus, and calcaneus have also been reported and therefore should be taken into account 9–13 …”

mentioning

confidence: 99%

“…9 However, other joints such as the jaw, humeral head, knee, talus, and calcaneus have also been reported and therefore should be taken into account. [9][10][11][12][13] It has been observed that both SARS-CoV-1 and SARS-CoV-2 enter cells through the angiotensin-converting enzyme 2 receptor. Upon binding to the receptor, the mixing of viral and human membranes and the release of viral RNA into the cytoplasm occur, resulting in the translation of viral proteins and replication of viral RNA.…”

mentioning

confidence: 99%

Knee Osteonecrosis After Sars-Cov 2 Virus Infection

Muñoz García,

Jiménez Martín,

Hernández Herrero

2023

Am J Phys Med Rehabil

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Osteonecrosis after COVID-19 infection is a complex pathology with multifactorial origin. Factors such as infection itself with associated coagulopathy, as well as genetic mechanisms, and medications used for its treatment such as corticosteroids, may also be involved. The variability in the presentation makes diagnosis difficult, which, if done soon, can help delay progression and reduce morbidity and the need for surgery. This report presents a case of knee osteonecrosis in a female patient who did not have previous knee pathology on imaging tests. She was diagnosed by magnetic resonance imaging months after hospital admission for SARS-COV 2 pneumonia, which required high-dose corticosteroid treatment.

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A case series on Covid-19 infection and avascular necrosis of hip

Cited by 9 publications

References 7 publications

Is post-COVID osteonecrosis of jaw (PCONJ) Masquerading as osteomyelitis ? A largest unicentric report of 13 cases

Is post-COVID osteonecrosis of jaw (PCONJ) Masquerading as osteomyelitis ? A largest unicentric report of 13 cases

A Comprehensive Review of COVID-19 Infection and Steroid-Associated Treatment Bone Avascular Necrosis: A Multi-Study Analysis

Knee Osteonecrosis After Sars-Cov 2 Virus Infection

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