A CAUCASOID PEDIGREE DEMONSTRATING THE TRANSMISSION OF A Gm<sup>1, 2, 17; 5, 13, 14</sup> HAPLOTYPE

Information related to 31 protein genetic systems was obtained for 307 individuals affiliated with the Cinta Larga, Karitiana, Surui and Kararaô Indians of northern Brazil. In terms of genetic distances the Cinta Larga showed more similarities with the Karitiana (both are Tupi-speaking tribes), while at a more distant level the Surui clustered with the Kararaô. The latter, a Cayapo subgroup, showed a completely different genetic constitution from the other subgroups of this same tribe. Both the Kararaô and Karitiana are small, remnant populations, and their gene pools have presumably been severely affected by random and founder effects. These results were incorporated with those of 25 other Amazonian Indian tribes, and analysis by two multivariate techniques confirmed a previously observed geographical dichotomy, suggesting either that the Amazon river constitutes a barrier to north-south gene flow or that latitudinally different past migrations entered the region from the west.

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QUANTITATIVE STUDIES OF Gm ALLOTYPES:V. SIMULTANEOUS PRESENCE OF LATENT Gm ALLOTYPES AND DEFICIENT Gm GENES IN A FAMILY WITH HYPOGAMMAGLOBULINAEMIC PROBANDS

Salier

Rivat

Daveau

et al. 1980

Int J Immunogenetics

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Summary A study of Gm allotypes in a Caucasoid family with hypogammaglobulinaemic probands, showed qualitative (unexpected or lacking Gm allotypes) and quantitative (increased or decreased Gm contents) abnormalities in many relatives. Part of these observations can be most probably accounted for by inheritance of a Gm1,17;5,28 haplotype, not described in Caucasians yet, and by an in vivo expression of latent Gm genes.

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A CAUCASOID PEDIGREE DEMONSTRATING THE TRANSMISSION OF A Gm^{1, 2, 17; 5, 13, 14} HAPLOTYPE

Abstract: SUMMARY Data illustrating the inheritance of a Gm1, 2, 17; 5, 13, 14 haplotype in a Caucasian family are presented. The mother and two children are heterozygous for this unusual haplotype. The possible origin of the haplotype is discussed.

Cited by 3 publications

References 7 publications

Gm and Km frequencies in a Portugese population

Gm and Km frequencies in a Portugese population

Further blood genetic studies on Amazonian diversity—Data from four Indian groups

QUANTITATIVE STUDIES OF Gm ALLOTYPES:V. SIMULTANEOUS PRESENCE OF LATENT Gm ALLOTYPES AND DEFICIENT Gm GENES IN A FAMILY WITH HYPOGAMMAGLOBULINAEMIC PROBANDS

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A CAUCASOID PEDIGREE DEMONSTRATING THE TRANSMISSION OF A Gm1, 2, 17; 5, 13, 14 HAPLOTYPE

Abstract: SUMMARY Data illustrating the inheritance of a Gm1, 2, 17; 5, 13, 14 haplotype in a Caucasian family are presented. The mother and two children are heterozygous for this unusual haplotype. The possible origin of the haplotype is discussed.

Cited by 3 publications

References 7 publications

Gm and Km frequencies in a Portugese population

Gm and Km frequencies in a Portugese population

Further blood genetic studies on Amazonian diversity—Data from four Indian groups

QUANTITATIVE STUDIES OF Gm ALLOTYPES:V. SIMULTANEOUS PRESENCE OF LATENT Gm ALLOTYPES AND DEFICIENT Gm GENES IN A FAMILY WITH HYPOGAMMAGLOBULINAEMIC PROBANDS

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A CAUCASOID PEDIGREE DEMONSTRATING THE TRANSMISSION OF A Gm^{1, 2, 17; 5, 13, 14} HAPLOTYPE